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CAS: 78-27-3
分子式: C8H12O
分子量: 124.18
沸点: 180 °C(lit.)
熔点: 30-33 °C(lit.)
中文名称: 
1-乙炔基-1-环己醇
乙炔环己醇
1-乙炔基-1-环已醇
1-乙炔基环己醇
英文名称: 
1-ethynyl-Cyclohexanol
(1-hydroxycyclohexyl)ethyne
1-ethynyl-1-cyclohexanol
1-ethynylcyclohexan-1-ol
1-ethynylcyclohexanol
1-ethynyl-cyclohexano
nsc 8194
1-ethynyl-cyclohexanol
Cyclohexanol,1-ethynyl-
1-ethvnvl-1-cvclohexanol
Cyclohexyl ethynyl carbinol
展开更多英文名
性质描述: 白色结晶。熔点30-31℃,沸点180℃,66℃(1.07kPa),折光率1.4820(20℃)。
生产方法: 将干燥的乙炔通入液氨中,同时加入钠,并滴加环已酮。加料完毕,将反应混合物放置20h,使氨挥发尽。加入冰水分解混合物中的固体残留物,然后用50%硫酸酸化。取有机层,水层用乙醚提取,将有机层与乙醚提取液混合,蒸除乙醚后减压蒸馏,收集(18.67kPa)馏分,得1-乙炔基-1-环已醇,收率65-74%。
用途: 用于有机合成。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
E742959MACKLIN1-乙炔基-1-环己醇Standard for GC, ≥99.8%(GC)128元/1g;   展开
储存:室温, 避光
状态:液体
E809391MACKLIN1-乙炔基-1-环己醇99%29元/5g;   42元/25g;   91元/100g;   340元/500g;   640元/1kg;   1580元/2.5kg;   3100元/5kg;   6100元/10kg;   展开
储存:室温, 避光
状态:无色或灰白色固体或液体
折射率:1.481-1.484
E0297TCI1-Ethynyl-1-cyclohexanol>98.0%(GC)220元/25G;   1630元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C8H12O = 124.18
外观与形状(20℃)固体
Reaxys-RN471404
PubChem物质ID87569564
SDBS (AIST Spectral DB)4706
MDL编号MFCD00003858

技术规格

AppearanceWhite to Orange to Green powder to crystaline
Purity(GC)min. 98.0 %
Solubility in Methanolalmost transparency

物性(参考值)

熔点31 ℃
沸点174 ℃
水溶性微溶
在水中的溶解度10 g/l   20 ℃
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词危险
危险性说明H311 : 皮肤接触会中毒。
H302 : 吞咽有害。
H316 : 造成轻微皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P361 + P364 : 立即脱掉所有沾染的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P302 + P352 + P312 : 如皮肤沾染:用水充分清洗。如感觉不适,呼叫急救中心/医生。
P405 : 存放处须加锁。

相关法规

RTECS#GV9100000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
122225J&K1-Ethynyl-1-cyclohexanol99%, 色号 25 APHA238元/100G;   899元/500G;   展开

基本信息

分子式C8H12O
分子量124.18
熔点30-33
沸点180
闪点73
密度0.967
MDL编码MFCD00003858
Beilstein471404
Merck10,3810
EINECS 编号201-100-9
存储条件Room temperature

安全信息

图形或危害标志
提示语Danger
危险说明H302
H311
防范说明P280
P312
UN号码2811
危险分类6.1
包装等级III
WGK1
RTECSGV9100000
TSCA
210832J&K1-Ethynyl-1-cyclohexanol97%170元/100G;   705元/500G;   展开

基本信息

分子式C8H12O
分子量124.18
熔点30-33
沸点180
闪点73
密度0.967
MDL编码MFCD00003858
Beilstein471404
Merck10,3810
EINECS 编号201-100-9

安全信息

图形或危害标志
提示语Danger
危险说明H302
H311
H315
H319
防范说明P280
P305+P351+P338
P312
UN号码2811
危险分类6.1
包装等级III
WGK1
RTECSGV9100000
TSCA
938555J&K1-Ethynyl-1-cyclohexanol99%228元/100G;   展开

基本信息

分子式C8H12O
分子量124.18
熔点30-33
沸点180
闪点73
密度0.967
MDL编码MFCD00003858
Beilstein471404
Merck10,3810
EINECS 编号201-100-9

安全信息

图形或危害标志
提示语Danger
危险说明H302
H311
H315
H319
防范说明P280
P301
P312+P330
P302+P352+P312
P305+P351+P338
UN号码2811
危险分类6.1
包装等级III
WGK1
RTECSGV9100000
TSCA
L12591Alfa Aesar1-Ethynylcyclohexanol99%743元/100g;   2839元/500g;   展开

应用
1-Ethynylcyclohexanol is used in organic synthesis, pharmaceuticals and agrochemicals.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00003858

EINECS
201-100-9

分子式
C8H12O

分子量
124.18

熔点
30-33°

沸点
180°

闪点
73°(163°F)

密度
0.973

折射率
1.4830

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Soluble in water (10g/L at 20°C), diethyl ether, alcohols, esters, and ketone.

Beilstein
471404

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H311-H319
Harmful if swallowed.Toxic in contact with skin.Causes serious eye irritation.

Precautionary Statements
P280-P305+P351+P338-P301+P312a-P321-P405-P501a
Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
21/22-36
Harmful in contact with skin and if swallowed.Irritating to eyes.

安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
GV9100000

TSCA

C11910Alfa Aesar1-Ethynyl-1-cyclohexanol99+%624元/100g;   2296元/500g;   9060元/2.5kg;   展开

基本信息

Ref#
11910

MDL
MFCD00003858

EINECS
201-100-9

分子式
C8 H12 O

分子量
124.18

熔点
30-33°

沸点
180°

闪点
73°(163°F)

密度
0.973

折射率
1.4830

形态
Low melting solid

Beilstein
471404

安全信息

危险等级
6.1

包装组
III

危险类别
21/22-36
Harmful in contact with skin and if swallowed.Irritating to eyes.

安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste

RTECS
GV9100000

TSCA

E51406Sigma-Aldrich1-Ethynyl-1-cyclohexanol≥99%472.6元/100 ML;   3283.42元/1 L;   15328.5元/5 L;   44443.6元/20 L;   展开

产品说明

应用

1-乙炔基-1-环己醇 (ECHO) 在常温下可在催化量的氯化钌存在下发生乙酰化反应。可用于合成对组织蛋白酶 B 具有强效抑制活性的新型有机碲 (IV) 化合物。过渡金属催化剂引发的 ECHO 聚合反应导致了 ECHO 聚合体的形成。它也可以通过插入 M-H 键与转换金属氢化物反应形成乙烯基衍生物。

包装

1 L in poly bottle
100 mL in poly bottle
5, 20 L in steel drum

基本信息

线性分子式HC≡CC6H10OH
分子量124.18
Beilstein471404
EC 号201-100-9
MDL编号MFCD00003858
PubChem化学物质编号24894607
NACRESNA.22

产品性质

蒸汽压<1 mmHg ( 20 ℃)
质量水平200
测定≥99%
bp180 ℃ (lit.)
mp30-33 ℃ (lit.)
密度0.967 g/mL at 25 ℃ (lit.)
SMILES stringOC1(CCCCC1)C#C
InChI1S/C8H12O/c1-2-8(9)6-4-3-5-7-8/h1,9H,3-7H2
InChI keyQYLFHLNFIHBCPR-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H302 - H311 - H315 - H319
预防措施声明P280 - P301 + P312 + P330 - P302 + P352 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 1
闪点(F)163.4 °F - closed cup
闪点(C)73 ℃ - closed cup
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
8.41522Sigma-Aldrich1-Ethynylcyclohexanolfor synthesis42591.3元/25 L;   展开

产品说明

分析说明

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.972 - 0.979
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

基本信息

经验(实验)分子式C8H12O
分子量124.18
MDL编号MFCD00003858
EC索引号201-100-9

产品性质

质量水平200
蒸汽压1 hPa ( 50 ℃)
测定≥98.0% (GC)
自燃温度365 ℃
效能583 mg/kg LD50, oral (Rat)
973 mg/kg LD50, skin (Rabbit)
expl. lim.1.3-8.7 % (v/v)
pH值(酸碱度)7 (20 ℃, 1 g/L in H2O)
bp180 ℃/1013 hPa
mp30-32 ℃
转变温度flash point 73 ℃
溶解性 10 g/L
密度0.976 g/cm3 at 20 ℃
储存温度2-30℃
InChI1S/C8H12O/c1-2-8(9)6-4-3-5-7-8/h1,9H,3-7H2
InChI keyQYLFHLNFIHBCPR-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H302 - H311 - H315 - H319
预防措施声明P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
闪点(F)163.4 °F - closed cup
闪点(C)73 ℃ - closed cup
544440Fluorochem1-Ethynyl-1-cyclohexanol98%220元/25g;   展开

基本信息

CAS Number78-27-3
MDL NumberMFCD00003858
Melting Point30-32℃
Density0.967

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H311: Toxic in contact with skin.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P361: Remove/Take off immediately all contaminated clothing.
P362: Take off contaminated clothing and wash before reuse.
P363: Wash contaminated clothing before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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