CAS 77286-66-9; 1-0-0ctadecyl-2-0-methyl-sn-gl ycero-3-phosphocholine

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CAS:

77286-66-9

分子式:

C27H58NO6P

分子量:

523.73

英文名称:

1-0-0ctadecyl-2-0-methyl-sn-gl ycero-3-phosphocholine

1-o-octadecyl-2-o-methyl-sn-glycero-3-phosphocholine

用途:

Edelfosine acts as a precursor for alkyl-lysophospholipids. It possesses apoptotic action against several cancer cells such as prostate, leukemia, brain and lung tumors. It is associated with cellular transport system, signaling transducing systems, cytokine synthesis and lipid metabolism. Edelfosine is known to control intracellular calcium levels. It is not mutagenic and its anti-tumor action requires its incorporation into the cell. Edelfosine is also found to block the replication of human immunodeficiency virus type I (HIV-I).

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

O921050

MACKLIN

1-O-十八烷基-2-O-甲基-SN-甘油-3-磷酸

1482元/5mg;

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储存：−20°C
状态：白色蜡状固体

999995P

Avanti

Edelfosine

Avanti Polar Lipids 999995P, powder

1192.61元/5 MG;

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产品说明

应用

Edelfosine or 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine might be used:

as a non-hydrolysable LysoPC (phospholipid) analog for analyzing its ability to block sexual commitment in Plasmodium falciparum
in multilamellar vesicle preparation, to study its effect on model membranes
in the selection and screening of mutagenized cells, having the ability to inhibit the transport of alkylphosphocholine drugs across the plasma membrane

生化/生理作用

Edelfosine acts as a precursor for alkyl-lysophospholipids. It possesses apoptotic action against several cancer cells such as prostate, leukemia, brain and lung tumors. It is associated with cellular transport system, signaling transducing systems, cytokine synthesis and lipid metabolism. Edelfosine is known to control intracellular calcium levels. It is not mutagenic and its anti-tumor action requires its incorporation into the cell. Edelfosine is also found to block the replication of human immunodeficiency virus type I (HIV-I).

包装

5 mL Clear Glass Sealed Ampule (999995P-5mg)

基本信息

经验(实验)分子式	C₂₇H₅₈NO₆P
分子量	523.73
NACRES	NA.25

产品性质

形式	powder
包装	pkg of 1 × 5 mg (999995P-5mg)
manufacturer/tradename	Avanti Polar Lipids 999995P
运输	dry ice
储存温度	−20℃
SMILES string	[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC)COCCCCCCCCCCCCCCCCCC)=O
InChI	1S/C10H24NO5P/c1-6-10(14-5)9-16-17(12,13)15-8-7-11(2,3)4/h10H,6-9H2,1-5H3/t10-/m0/s1
InChI key	GVMCXWJIRSIWFJ-JTQLQIEISA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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