| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| M814084 | MACKLIN | 1-甲基吡唑-4-硼酸频哪醇酯 | 97% | 25元/250mg; 30元/1g; 52元/5g; 140元/25g; 535元/100g; | 展开 |
储存：2~8°C,易燃物区域 状态：粉末,晶体和/或块状 |
| M2339 | TCI | 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole | >98.0%(GC) | 320元/1G; 1235元/5G; | 展开 |
基本信息 | 纯度/分析方法 | >98.0%(GC) | | 分子式/分子量 | C10H17BN2O2 = 208.07 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 9903888 | | PubChem物质ID | 253659774 | | MDL编号 | MFCD03789259 |
技术规格 | Appearance | White to Light yellow powder to crystal | | Purity(GC) | min. 98.0 % | | Melting point | 60.0 to 64.0 ℃ |
物性(参考值) 安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
| | 防范说明 | P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
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| 509529 | J&K | 1-Methylpyrazole-4-boronic Acid Pinacol Ester | 98% | 121元/1G; 299元/5G; | 展开 |
基本信息 | 分子式 | C10H17BN2O2 | | 分子量 | 208.07 | | 熔点 | 59-64 | | MDL编码 | MFCD03789259 |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302
H315
H319
H335 | | 防范说明 | P261
P305+P351+P338 | | WGK | 3 | | TSCA | 否 |
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| H53139 | Alfa Aesar | 1-Methyl-1H-pyrazole-4-boronic acid pinacol ester | 97% | 941元/250mg; 3019元/1g; | 展开 |
应用
It is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer. 备注
Store in cool dry place. Ensure proper ventilation. Incompatible with oxidizing agents. 基本信息 MDL
MFCD03789259 分子式
C10H17BN2O2 分子量
208.07 熔点
59-64° 灵敏度
Ambient temperatures. 形态
Crystalline powder 溶解性
Slightly soluble in water. GHS危害和防范说明 GHS符号
Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. 安全信息 危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin. 安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves. 欧盟危险品标志
 TSCA
否 |
| C38296 | Alfa Aesar | 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 97+% | 999元/1g; 3430元/5g; 12756元/25g; | 展开 |
基本信息 Ref#
38296 MDL
03789259 分子式
C10 H17 B N2 O2 分子量
208.07 |
| 595314 | Sigma-Aldrich | 1-Methylpyrazole-4-boronic Acid Pinacol Ester | 95% | 501.66元/1 G; 1533.96元/5 G; 7398.39元/25 G; | 展开 |
产品说明 应用 试剂用于 - Suzuki-Miyaura交叉偶联反应
- 酯交换反应
用于制备 - 氨基噻唑类(γ)-分泌酶调节剂
- 氨基吡啶-吲哚甲酰胺，作为骨髓增生性疾病治疗的潜在 JAK2 抑制剂
- 吡啶衍生物作为 TGF-β1 和激活素 A 信号传导抑制剂
- MK-2461 类似物作为 c-Met 激酶抑制剂治疗癌症
稳定的硼酸替代品，用于Suzuki-Miyaura钯催化交叉偶联 包装 1, 5, 25 g in glass bottle 基本信息 | 经验(实验)分子式 | C10H17BN2O2 | | 分子量 | 208.07 | | MDL编号 | MFCD03789259 | | PubChem化学物质编号 | 24881568 | | NACRES | NA.22 |
产品性质 | 质量水平 | 100 | | 测定 | 95% | | mp | 59-64 ℃ (lit.) | | SMILES string | Cn1cc(cn1)B2OC(C)(C)C(C)(C)O2 | | InChI | 1S/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-12-13(5)7-8/h6-7H,1-5H3 | | InChI key | UCNGGGYMLHAMJG-UHFFFAOYSA-N |
安全信息 | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
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| 010814 | Fluorochem | 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-1H-pyrazole | 98% | 220元/1g; 264元/5g; 814元/25g; 2090元/100g; | 展开 |
基本信息 | CAS Number | 761446-44-0 | | MDL Number | MFCD03789259 | | Boiling Point | 308.3℃ | | Melting Point | 62-67℃ | | Density | 1.05 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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