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CAS: 73226-73-0
分子式: C5H11NNaO5P
分子量: 219.11
熔点: 184-186°C
英文名称: 
fr-900098 monosodium salt
(3-(acetylhydroxyamino)propyl)-phosphonic acid
brn 2096083
p-[3-(acetylhydroxyamino)propyl]-phosphonic acid
用途: 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
F920948MACKLIN(3-(乙酰羟胺基)丙基)-膦酸≥97% (NMR)1817元/5mg;   展开
储存:−20°C
状态:固体
F8307Sigma-AldrichFR-900098 monosodium salt≥97% (NMR)1795.68元/5 MG;   7227.99元/25 MG;   展开

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.

基本信息

经验(实验)分子式C5H11NNaO5P
分子量219.11
MDL编号MFCD17215926
PubChem化学物质编号329799770
NACRESNA.77

产品性质

质量水平100
测定≥97% (NMR)
形式powder
储存条件desiccated
protect from light
颜色 white to light brown
溶解性H2O: ≥20 mg/mL
储存温度−20℃
SMILES string[Na+].CC(=O)N(O)CCCP(O)([O-])=O
InChI1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
InChI keyLCFXFDGYDKNWMD-UHFFFAOYSA-M

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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