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CAS: 723-46-6
分子式: C10H11N3O3S
分子量: 253.28
熔点: 166 °C
中文名称: 
磺安甲恶唑
3-对氨基苯磺酰胺基-5-甲基恶唑
新诺明
磺安甲噁唑
新明磺
磺胺甲基异噁唑
3-对氨基苯磺酰胺基-5-甲基噁唑
磺胺甲恶唑
英文名称: 
N1-(5-methyl-3-isoxazolyl)sulfanilamide
sulfanilamide,N1-(5-methyl-3-isoxazolyl)-
benzenesulfonamide,4-amino-N-(5-methyl-3-isoxazolyl)-
n'-(5-methyl-3-isoxazolyl)-sulfanilamid
3-(p-aminophenylsulfonamido)-5-methylisoxazole
3-(para-aminophenylsulphonamido)-5-methylisoxazole
3-sulfanilamido-5-methylisoxazole
3-sulphanilamido-5-methylisoxazole
4-amino-n-(5-methyl-3-isoxazolyl)benzenesulfonamide
5-methyl-3-sulfanilamidoisoxazole
5-methyl-3-sulfanylamidoisoxazole
SMZ
5-methyl-3-sulphanil-amidoisoxazole
a047
azo-gantanol
4-amino-n-(5-methyl-3-isoxazolyl)-benzenesulfonamid
gantanol
metoxal
ms 53
n'-(5-methyl-3-isoxazole)sulfanilamide
n'-(5-methyl-3-isoxazolyl)sulfanilamide
n'-(5-methylisoxazol-3-yl)sulphanilamide
n(1)-(5-methyl-3-isoxazolyl)sulfanilamide
n(sup 1)-(5-methyl-3-isoxazolyl)sulphanilamide
radonil
ro 4-2130
sinomin
sulfamethalazole
sulfamethoxazol
sulfamethoxazole
sulfamethoxizole
sulfamethylisoxazole
n(1)-(5-methyl-3-isoxazolyl)-sulfanilamid
sulfisomezole
sulpha-methoxizole
sulphamethoxazol
sulphamethoxazole
sulphamethylisoxazole
展开更多英文名
性质描述: 白色结晶性粉末。熔点167℃,易溶于稀盐酸、氢氧化钠溶液或氨水,几乎不溶于水。无臭,味微苦。
生产方法: 由5-甲基异噁唑-3-甲酰胺经降解、缩合、水解而得。
用途: 该品能阻细菌生长,对葡萄球菌及大肠杆菌作用特别强,治疗泌尿道感染以及禽堆乱效果好。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
S861458MACKLIN磺胺甲恶唑生物技术级66元/1g;   180元/5g;   402元/25g;   806元/100g;   2770元/500g;   展开
储存:2-8ºC
状态:白色到灰白色固体
S817665MACKLIN磺胺甲噁唑分析对照品,≥99.5%288元/250mg;   展开
储存:2~8°C
状态:白色-几乎白色晶体-粉末
S817664MACKLIN磺胺甲噁唑98%30元/5g;   60元/25g;   133元/100g;   394元/500g;   719元/1kg;   1604元/2.5kg;   展开
储存:2~8°C
状态:白色到灰白色粉末或固体或块状
S0361TCISulfamethoxazole>98.0%(T)(HPLC)550元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C10H11N3O3S = 253.28
外观与形状(20℃)固体
应避免的情况
Reaxys-RN226453
PubChem物质ID87575873
SDBS (AIST Spectral DB)18812
Merck Index (14)8918
MDL编号MFCD00010546

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point169.0 to 172.0 ℃
Solubility in Methanolalmost transparency

物性(参考值)

熔点170 ℃
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#WP0700000
587147J&KSulfamethoxazole98%66元/5G;   100元/25G;   展开

基本信息

分子式C10H11N3O3S
分子量253.28
熔点169-172
MDL编码MFCD00010546
Beilstein6732984
Merck14,8918
EINECS 编号211-963-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H317
H319
H335
防范说明P261
P280
P305+P351+P338
P333+P313
P337+P313
WGK2
RTECSWP0700000
R10834Alfa AesarSulfamethoxazole Standard solution100ppm168元/1ml;   展开

安全信息

危险等级
3

R11921Alfa AesarSulfamethoxazole,1000ppm352元/1ml;   展开

安全信息

危险等级
3

PHR1126SupelcoSulfamethoxazolePharmaceutical Secondary Standard; Certified Reference Material855.65元/1 G;   展开

产品说明

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Sulfamethoxazole is one of the most effective sulfa drugs used for treating urinary infections in humans.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Sulfamethoxazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by square-wave voltammetry, and visible/UV spectrophotometry.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6910 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
EC 号211-963-3
MDL编号MFCD00010546
PubChem化学物质编号329823147
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 314
traceable to PhEur S2100000
traceable to USP 1631001
储存温度2-30℃
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361d
预防措施声明P201 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
S2100000SulfamethoxazoleEuropean Pharmacopoeia (EP) Reference Standard1583.12元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
MDL编号MFCD00010546
PubChem化学物质编号329824505
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361d
预防措施声明P201 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
31737SupelcoSulfamethoxazoleVETRANAL®, analytical standard571.28元/250 MG;   展开

产品说明

一般描述

Sulfamethoxazole is a bacteriostatic antibiotic used in treating coccidiosis, diarrhea and gastroenteritis in humans and is also a known veterinary drug. Sulfamethoxazole in combination with trimethoprim is effective in treating pneumonia. Sulfamethoxazole acts by blocking the folic acid metabolism to produce synergistic antibacterial activity.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethoxazole may be used as a reference standard for the determination of the analyte in:

  • Bovine milk by high-performance liquid chromatography method.
  • Pharmaceutical formulations and biological samples by capillary electrophoresis (CE) with end-column electrochemical detection (EC).

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
EC 号211-963-3
MDL编号MFCD00010546
PubChem化学物质编号329753910
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361fd
预防措施声明P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
76177SupelcoSulfamethoxazolecertified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland1104.89元/100 mg;   展开

产品说明

一般描述

Chemical structure: sulfonamide
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

法律信息

TraceCERT is a registered trademark of sigma-aldrich Co. LLC

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
EC 号211-963-3
MDL编号MFCD00010546
PubChem化学物质编号329766577
NACRESNA.24

产品性质

质量水平300
等级certified reference material
TraceCERT®
产品线TraceCERT®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361fd
预防措施声明P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
S7507SupelcoSulfamethoxazole630.94元/10 g;   3254.05元/100 g;   展开

产品说明

一般描述

磺胺甲恶唑是抑菌抗生素,属于磺胺类。广泛用于治疗肺囊虫病、 球虫病、胃肠炎、腹泻和呼吸系统疾病(如肺炎等)。

应用

磺胺甲恶唑用作分析参考标准品,使用分析 和微生物测定技术,定量牛乳样品中的分析物。
有关合适仪器技术的更多信息,请参考产品的分析证书。如需进一步支持,请联系技术服务。

生化/生理作用

通过抑制二氢叶酸合成酶阻断二氢叶酸合成的磺胺类抗生素。
作用方式:在原核生物中抑制叶酸合成。
抗菌谱:革兰氏阳性菌、革兰氏阴性菌、衣原体
抗性机理:二氢叶酸合成酶或叶酸合成替代路径的改变。

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
EC 号211-963-3
MDL编号MFCD00010546
PubChem化学物质编号329824585

产品性质

等级analytical standard
质量水平100
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361fd
预防措施声明P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
BP314SulfamethoxazoleBritish Pharmacopoeia (BP) Reference Standard1952.55元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
EC 号211-963-3
MDL编号MFCD00010546
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361d
预防措施声明P201 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1631001USPSulfamethoxazoleUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C10H11N3O3S
分子量253.28
Beilstein6732984
MDL编号MFCD00010546
PubChem化学物质编号329751182
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
InChI keyJLKIGFTWXXRPMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H317 - H361d
预防措施声明P201 - P280 - P302 + P352 - P308 + P313
危险分类Repr. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
999559AmethystSulfamethoxazole98%, 试剂级52元/5G;   70元/25G;   208元/100G;   782元/500G;   展开

基本信息

分子式C10H11N3O3S
分子量253.28
熔点166-169
MDL编码MFCD00010546
Beilstein6732984
Merck14,8918
EINECS 编号211-963-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H317
H319
H335
防范说明P261
P280
P305+P351+P338
WGK2
RTECSWP0700000
236656Fluorochem4-Amino-N-(5-methylisoxazol-3-yl)benzenesulfonamide98%286元/5g;   616元/25g;   1100元/100g;   8910元/1kg;   展开

基本信息

CAS Number723-46-6
MDL NumberMFCD00010546
Melting Point170℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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