CAS: | 72214-67-6 | |||||
分子式: | C8H9Cl3N2S | |||||
分子量: | 271.59 | |||||
英文名称: |
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货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||
D724996 | MACKLIN | S-2,4-二氯苄基 异硫脲 盐酸盐 | 99% | 234元/50mg; 398元/100mg; 755元/250mg; | 展开 | ||||||||||||||||||||||||||||||||||
储存:室温, 惰性气体 | |||||||||||||||||||||||||||||||||||||||
R7532 | Sigma-Aldrich | RRD-251 hydrochloride | ≥98% (HPLC) | 489.22元/5 MG; 2426.51元/25 MG; | 展开 | ||||||||||||||||||||||||||||||||||
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 RRD-251 hydrochloride is a reversible, potent, and selective disruptor of Rb/Raf-1 interaction. The retinoblastoma tumor suppressor protein (Rb) controls the G1-S boundary by repressing the transcriptional activity of the E2F family of transcription factors. Raf-1 kinase binds and phosphorylates Rb early in the G1 phase. RRD-251 significantly inhibits angiogenesis and tumor growth in vivo in an Rb-dependent manner. RRD-251 does not inhibit the binding of B-Raf to Rb and Raf-1 to Mek1/2. Also, RRD-251 does not affect the kinase activities associated with cyclin D, cyclin E, or Raf-1. 基本信息
产品性质
安全信息
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391860 | Fluorochem | 2,4-dichlorobenzyl imidothiocarbamate hydrochloride | 95% | 4510元/1g; 15730元/5g; | 展开 | ||||||||||||||||||||||||||||||||||
基本信息
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