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CAS: 719-59-5
分子式: C13H10ClNO
分子量: 231.68
沸点: 207℃
熔点: 96-100℃
中文名称: 
2-苯甲酰基-4-氯苯胺
氨基酮
2-氨基-5-氯二苯甲酮
2-氨基-5-氯苯并苯酮
英文名称: 
4-Chloro-2-benzoylaniline
2-Amino-5-chlorodiphenylone
(2-amino-5-chlorophenyl)phenyl-Methanone
2-Benzoyl-4-chloroaniline
(2-amino-5-chlorophenyl)phenylmethanone
2-amino-5-chlorobenzophenone
(2-amino-5-chlorophenyl)phenyl-methanon
2-amino-5-chloro diphenylone
2-amino-5-chlorobenzopheno ne
Methanone,(2-amino-5-chlorophenyl)phenyl-
性质描述: 黄色棱柱状结晶。熔点99℃。
生产方法: (1)由对氯苯胺与苯甲酰氯反应制得。先将对氯苯加入搪玻璃反应锅中,在70℃以下,投入无水氯化锌,在搅拌下滴加苯甲酰氯,然后升温,在195-205℃保温2h后,用90-95℃的热水洗涤五次(水层及洗液回收苯甲酸与氯化锌)在100℃左右,将硫酸徐徐加入,在142℃保温40min。趁热将料液注入0-5℃水中,析出固体。在搅拌下,用液碱调节pH不高于1,在20-25℃时过滤。滤液回收对氯苯胺。滤饼混悬于水中,中和至pH=6,滤干,用水洗至中性,烘干得粗品。然后加6-7倍乙醇,6%活性炭,回流30min,过滤结晶,烘干而得精品。(2)对硝基氯苯与氰苄环合得异噁唑,再开环,还原而得。
用途: 医药中间体。生产利眠安、安定等药物。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A800087MACKLIN2-氨基-5-氯二苯甲酮98%30元/25g;   62元/100g;   265元/500g;   1215元/2.5kg;   4188元/10kg;   展开
储存:室温
状态:白色到浅黄色粉末或晶体
A0079TCI2-Amino-5-chlorobenzophenone>98.0%(T)155元/25G;   1150元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C13H10ClNO = 231.68
外观与形状(20℃)固体
Reaxys-RN475640
PubChem物质ID87561776
SDBS (AIST Spectral DB)6471
MDL编号MFCD00007839

技术规格

AppearanceLight yellow to Yellow to Green powder to crystal
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 98.0 %
Melting point96.0 to 100.0 ℃

物性(参考值)

熔点98 ℃
水溶性不溶
溶解性(可溶于)甲醇,苯,氯仿,乙醇,丙酮,甲苯

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#PC4933500
406575J&K2-Amino-5-chlorobenzophenone98%115元/25G;   314元/100G;   1064元/500G;   展开

基本信息

分子式C13H10ClNO
分子量231.68
熔点96-98
MDL编码MFCD00007839
Beilstein475640
EINECS 编号211-949-7

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSPC4933500
TSCA
A15720Alfa Aesar2-Amino-5-chlorobenzophenone98+%895元/100g;   2565元/500g;   10897元/2500g;   展开

应用
It is used in the heterocyclic syntheses based on the reactions of dimethyl acetylenedicarboxylate.

备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00007839

EINECS
211-949-7

分子式
C13H10ClNO

分子量
231.68

熔点
96-99°

闪点
211°(412°F)

密度
1.33

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Solubility in methanol gives very faint turbidity. Soluble in DMSO.

Beilstein
475640

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
PC4933500

TSCA

C10334Alfa Aesar2-Amino-5-chlorobenzophenone98%501元/25g;   946元/100g;   3945元/500g;   展开

基本信息

Ref#
10334

MDL
7839

分子式
C13 H10 Cl N O

分子量
231.68

闪点
211

形态
Powder

1022808USP2-Amino-5-chlorobenzophenoneUnited States Pharmacopeia (USP) Reference Standard11011.4元/25 MG;   展开

产品说明

一般描述

2-Amino-5-chlorobenzophenone is a organic nonlinear optical material.

应用

It was used in the determination of chlordiazepoxide and mebeverine HCl using HPLC method.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式H2NC6H3(Cl)COC6H5
分子量231.68
Beilstein475640
MDL编号MFCD00007839
PubChem化学物质编号329748988
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp96-98 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringNc1ccc(Cl)cc1C(=O)c2ccccc2
InChI1S/C13H10ClNO/c14-10-6-7-12(15)11(8-10)13(16)9-4-2-1-3-5-9/h1-8H,15H2
InChI keyZUWXHHBROGLWNH-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
A45564Sigma-Aldrich2-Amino-5-chlorobenzophenone98%240.94元/25 G;   409.29元/100 G;   展开

基本信息

线性分子式H2NC6H3(Cl)COC6H5
分子量231.68
Beilstein475640
EC 号211-949-7
MDL编号MFCD00007839
PubChem化学物质编号24890879
NACRESNA.22

产品性质

质量水平100
测定98%
mp96-98 ℃ (lit.)
SMILES stringNc1ccc(Cl)cc1C(=O)c2ccccc2
InChI1S/C13H10ClNO/c14-10-6-7-12(15)11(8-10)13(16)9-4-2-1-3-5-9/h1-8H,15H2
InChI keyZUWXHHBROGLWNH-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1507Supelco2-Amino-5-chlorobenzophenonePharmaceutical Secondary Standard; Certified Reference Material3234.39元/200 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA3314 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式H2NC6H3(Cl)COC6H5
分子量231.68
Beilstein475640
EC 号211-949-7
MDL编号MFCD00007839
PubChem化学物质编号329823426
NACRESNA.24

产品性质

质量水平100
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 200 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp96-98 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1022808
储存温度2-30℃
SMILES stringNc1ccc(Cl)cc1C(=O)c2ccccc2
InChI1S/C13H10ClNO/c14-10-6-7-12(15)11(8-10)13(16)9-4-2-1-3-5-9/h1-8H,15H2
InChI keyZUWXHHBROGLWNH-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
043861Fluorochem2-Amino-5-chlorobenzophenone98%220元/25g;   352元/100g;   展开

基本信息

CAS Number719-59-5
MDL NumberMFCD00007839
Melting Point98-100℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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