CAS 60-92-4; 腺苷环磷酸酯; 3',5'-Cyclic AMP

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包装、参考价格

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A804842

MACKLIN

腺苷环磷酸酯

99%

36元/500mg; 47元/1g; 190元/5g; 756元/25g; 2888元/100g;

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储存：-20 °C
状态：白色到浅黄色粉末

A2381

TCI

Adenosine 3',5'-Cyclic Monophosphate

>99.0%(HPLC)

240元/1G; 1050元/5G;

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基本信息

纯度/分析方法	>99.0%(HPLC)
分子式/分子量	C₁₀H₁₂N₅O₆P = 329.21
外观与形状(20℃)	固体
储存温度	<0℃
应避免的情况	加热
Reaxys-RN	52645
PubChem物质ID	135727004
Merck Index (14)	2708
MDL编号	MFCD00005845

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 99.0 area%
Purity(with Total Nitrogen)	min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D	-48.0 to -52.0 deg(C=0.7,H2O)
Water	max. 12.0 %

物性(参考值)

熔点	220 ℃
比旋光度 [α]D	-50° (C=0.7,H2O)

相关法规

RTECS#

AU7357600

464651

J&K

Adenosine 3',5'-cyclophosphate

99%

240元/100mg; 569元/500MG; 1033元/1G; 4647元/5G;

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基本信息

分子式	C₁₀H₁₂N₅O₆P
分子量	329.21
熔点	260
MDL编码	MFCD00005845
Beilstein	52645
EINECS 编号	200-492-9
存储条件	Freezer -20℃

安全信息

防范说明	P260 P262
WGK	3
RTECS	AU7357600

A9501

Sigma-Aldrich

Adenosine 3′,5′-cyclic monophosphate

≥98.5% (HPLC), powder

3431.78元/1 G; 13194.3元/5 G; 32452.7元/25 G;

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产品说明

应用

腺苷3′,5′-环一磷酸已用于：

在胚胎脊髓神经细胞培养中作为细胞培养基补充剂
作为灌注研究中林格溶液的一个组成部分
在人肺癌细胞系中诱导神经内分泌分化

包装

1, 5, 25 g in poly bottle

生化/生理作用

环化腺苷酸依赖性蛋白激酶 (PKA) 的自然活化剂。cAMP 是一种重要的第二信使，并且在很多系统中与神经递质或激素诱导的受体激活相关。已有显示，cAMP/PKA 信号通路可抑制细胞增殖，诱导分化并导致细胞凋亡。

特点和优势

该化合物是用于ADME Tox和环核苷酸研究的特色产品。发现更多精选用于 ADME Tox 和环核苷酸研究的产品。了解更多有关用于其他研究领域的生物活性小分子的信息，请访问 sigma.com/discover-bsm。

基本信息

经验(实验)分子式	C₁₀H₁₂N₅O₆P
分子量	329.21
Beilstein	52645
EC 号	200-492-9
MDL编号	MFCD00005845
eCl@ss	32160414
PubChem化学物质编号	24278245
NACRES	NA.77

产品性质

质量水平	200
测定	≥98.5% (HPLC)
形式	powder
颜色	white
mp	260 ℃ (dec.) (lit.)
溶解性	H₂O: 10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
储存温度	−20℃
SMILES string	Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O
InChI	1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChI key	IVOMOUWHDPKRLL-KQYNXXCUSA-N
Gene Information	human ... OPRK1(4986)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

213436

Fluorochem

Adenosine-3',5'-cyclophosphate

95%

506元/1g; 1782元/5g; 2970元/10g; 5654元/25g;

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基本信息

CAS Number	60-92-4
MDL Number	MFCD00005845

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .