| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| P793971 | MACKLIN | 根皮素 | 10mM in DMSO | 198元/1ml; | 展开 |
储存：-20°C 状态：白色至极淡黄色-黄红色水晶-粉末 |
| P1966 | TCI | Phloretin | >98.0%(HPLC) | 475元/1G; 1420元/5G; | 展开 |
基本信息 | 纯度/分析方法 | >98.0%(HPLC) | | 分子式/分子量 | C15H14O5 = 274.27 | | 外观与形状(20℃) | 固体 | | 储存温度 | 0-10℃ | | 应避免的情况 | 光,加热 | | Reaxys-RN | 1887240 | | PubChem物质ID | 135727056 | | Merck Index (14) | 7326 | | MDL编号 | MFCD00002288 |
技术规格 | Appearance | White to Light yellow to Light orange powder to crystal | | Purity(HPLC) | min. 98.0 area% | | Purity(Neutralization titration) | min. 95.0 % |
物性(参考值) | 熔点 | 262 ℃(dec.) | | 水溶性 | 不溶 | | 溶解性(易溶于) | 丙酮,醇 | | 溶解度(极微溶) | 氯仿,苯 | | 溶解性(不溶于) | 乙醚 |
安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
| | 防范说明 | P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
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| 179501 | J&K | Phloretin | 98% | 260元/25MG; 688元/100MG; | 展开 |
基本信息 | 分子式 | C15H14O5 | | 分子量 | 274.27 | | 熔点 | 260-262 | | MDL编码 | MFCD00002288 | | Beilstein | 1887240 | | EINECS 编号 | 200-488-7 | | 存储条件 | Store at 2-8℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H315
H319
H335 | | 防范说明 | P261
P305+P351+P338 | | WGK | 3 | | TSCA | 否 |
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| L10991 | Alfa Aesar | Phloretin | 98% | 617元/25mg; 1628元/100mg; | 展开 |
应用
Topical antioxidant 基本信息 MDL
MFCD00002288 EINECS
200-488-7 分子式
C15H14O5 分子量
274.28 熔点
ca 263° dec. 灵敏度
Keep Cold. 形态
Powder Beilstein
1887240 Merck
14,7326 GHS危害和防范说明 GHS符号
Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. 安全信息 危险类别
36/37/38
Irritating to eyes, respiratory system and skin. 安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. TSCA
否 |
| C30765 | Alfa Aesar | Phloretin | 98% | 1115元/100mg; 6503元/500mg; | 展开 |
基本信息 Ref#
30765 MDL
2288 分子式
C15 H14 O5 分子量
274.27 |
| P7912 | Sigma-Aldrich | Phloretin | ≥99% | 763.48元/25 MG; 1491.11元/100 MG; 2979.41元/250 MG; | 展开 |
产品说明 一般描述 普拉染料根皮素属于二氢查耳酮类。
苹果中发现的主要多酚；根皮苷苷元。 应用 使用根皮素： - 研究其对2-[N-(7-硝基苯-2-乙二酸-1,3-二嗪农-4-基)氨基]-2-脱氧-d-葡萄糖(2-NBDG) 和 2-[N-(7-硝基苯-2-乙二酸-1,3-二嗪农-4-基)氨基]-2-脱氧-l-葡萄糖 (2-NBDLG)摄取的影响
- 培养细胞微泡，以在放射配基摄取分析中抑制GLUT1(葡萄糖转运蛋白1)介导的转运
- 作为KRH缓冲液的组成部分，体外抑制滋养层细胞对葡萄糖的摄取
包装 25, 100, 250 mg in poly bottle 生化/生理作用 根皮素能降低脂质双层的界面偶极能。根皮素通过抑制蛋白激酶C (PKC)活性和刺激程序性细胞死亡而具有抗肿瘤作用。研究发现其能抑制GLUT(葡萄糖转运蛋白)和水通道蛋白的转运功能。
阻断L型Ca2+通道；激活两栖动物有髓神经纤维中的Ca2+-激活K+通道。单羧酸转运蛋白抑制剂。
与连-二羰基化合物如乙二醛和甲基乙二醛反应，防止与生物大分子的细胞毒性结合。 基本信息 | 经验(实验)分子式 | C15H14O5 | | 分子量 | 274.27 | | Beilstein | 1887240 | | EC 号 | 200-488-7 | | MDL编号 | MFCD00002288 | | PubChem化学物质编号 | 24278652 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 测定 | ≥99% | | mp | ~260 ℃ | | 储存温度 | 2-8℃ | | SMILES string | Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 | | InChI | 1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 | | InChI key | VGEREEWJJVICBM-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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| 524488 | Sigma-Aldrich | Phloretin-CAS 60-82-2-Calbiochem | A cell-permeable inhibtor of protein kinase C (IC₅₀ = 20-50 µM). | 2165.23元/200 MG; | 展开 |
产品说明 一般描述 A cell-permeable inhibtor of protein kinase C (IC50 = 20-50 µM). Activates Ca2+-activated K+ channels in amphibian myelinated nerve fibers at micromolar concentrations. An inhibitor of myo-inositol uptake. Also inhibits L-type Ca2+ channel activity. A potent inhibitor of 5′-iodothyronine deiodinase. Antagonist of prostaglandin F2α receptors linked to phospholipase C in astrocytes. 包装 200 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes
Target IC50: 20-50 µM against protein kinase C
Product does not compete with ATP.
Reversible: no 警告 Toxicity: Irritant (B) 重悬 Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 1 month at -20°C. 其他说明 Berry, G.T., et al. 1994. Pediat. Res.35, 141.
Koh, D.S., et al. 1994. Neurosci. Lett. 165, 167.
Morreale de Escobar, G., et al. 1994. Endocrinology134, 2410.
Prevarskaya, N., et al. 1994. Mol. Cell. Neurosci.5, 699.
Kitanaka, J., et al. 1993. J. Neurochem.60, 704.
Wang, X., et al. 1993. Biochem. J.290, 249.
Benga, G., et al. 1992. Eur. J. Cell Biol.59, 219.
Jordan, M.L., and Wright, J. 1991. J. Surg. Res.50, 569. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C15H14O5 | | 分子量 | 274.27 | | MDL编号 | MFCD00002288 |
产品性质 | 质量水平 | 100 | | 测定 | ≥97% (TLC) | | 形式 | solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze | | 颜色 | white | | 溶解性 | acetone: soluble
ethanol: soluble
methanol: soluble | | 运输 | ambient | | 储存温度 | −20℃ | | InChI | 1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 | | InChI key | VGEREEWJJVICBM-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| PHL82624 | | Phloretin | phyproof® Reference Substance | 3048.57元/100 MG; | 展开 |
产品说明 一般描述 This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
苹果中发现的主要多酚；根皮苷苷元。 生化/生理作用 与连-二羰基化合物如乙二醛和甲基乙二醛反应，防止与生物大分子的细胞毒性结合。 法律信息 phyproof is a registered trademark of PhytoLab GmbH & Co. KG 基本信息 | 经验(实验)分子式 | C15H14O5 | | 分子量 | 274.27 | | Beilstein | 1887240 | | MDL编号 | MFCD00002288 |
产品性质 | 等级 | primary reference standard | | 产品线 | phyproof® Reference Substance | | 测定 | ≥95.0% (HPLC) | | 形式 | solid | | manufacturer/tradename | PhytoLab | | mp | ~260 ℃ | | SMILES string | Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1 | | InChI | 1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 | | InChI key | VGEREEWJJVICBM-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H315 - H319 - H335 | | 预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 002612 | Fluorochem | 2',4',6'-Trihydroxy-3-(4-hydroxyphenyl)-propiophenone | 98% | 286元/1g; 748元/5g; 1562元/25g; | 展开 |
基本信息 | CAS Number | 60-82-2 | | MDL Number | MFCD00002288 | | Melting Point | 260-262℃(dec.) |
安全信息 | 图形或危害标志 | | | 危险性说明 | H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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