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CAS: 60-32-2
分子式: C6H13NO2
分子量: 131.17
熔点: 205-212℃
中文名称: 
氨己酸
6-氨基己酸
英文名称: 
6-Amino-hexanoic acid
6-Amino-n-hexanoic acid
ε-Aminocapronsαure
aminocaproic acid
e-aminocaproic acid
ε-Aminocaproic acid
6-Aminohexanoic acid 1M solution
6-Aminohexanoic acid solution
H-6-Aca-OH
6-Amino caproic acid
.epsilon.-Aminocaproic acid
6-amino-hexanoic aci
177 j.d.
177 jd
6-aminocaproic acid
6-Amino-n-caproic-acid
6-aminohexanoic acid
Epsilonaminocaproic acid
acepramin
acepramine
acs
afibrin
amicar
amikar
aminokapron
caplamin
capralense
capramol
caprocid
caprolisin
cl 10304
cy 116
eaca
eaca kabi
eacs
epsamon
epsicapron
epsikapron
epsilcapramin
epsilon s
epsilon-aminocaproic acid
epsilon-aminohexanoic acid
epsilon-leucine
epsilon-norleucine
hemocaprol
hemopar
hepin
ipsilon
kyselina omega-aminokapronova
nsc-26154
omega-aminocaproic acid
omega-aminohexanoic acid
respramin
6-Amino-n-caproic acid
6-Amino-n-caproic acid;6-Aminohexanoic acid
展开更多英文名
性质描述: 白色结晶粉末。熔点204-206℃。易溶于水,微溶于甲醇,不溶于乙醇和醚。无臭,味苦。
生产方法: 己内酰胺水解而得。将己内酰胺、浓盐酸和3倍量蒸馏水加入反应罐内,搅拌,升温回流1.5h,控制温度103-106℃。反应毕,测定转化率应达95%以上。加蒸馏水稀释成10%浓度,得10%6-氨基己酸水解液。将水解液以每小时5-10L的流速均匀地流入离子交换柱[装001×7(732#)强酸性苯乙烯系阳离子交换树脂],进行吸附。流完后关闭出口,浸泡过夜。用蒸馏水洗涤离子交换柱,洗去盐酸(检查流出液至无氯离子)。然后,以每小时5-10L流速均匀流入3.5%氢氧化铵。流完后关闭流出口,浸泡过夜。次日继续边完氢氧化铵后,流入蒸馏水进行洗脱,收集含有6-氨基己酸的洗脱液。加活性炭脱色,过滤,滤液于47-70℃减压浓缩近干。趁热加入乙醇,搅拌析出结晶。冷却后甩滤得粗品。将粗品溶于蒸馏水,加活性炭在60℃脱色1h。趁热过滤。滤液减压浓缩近干。加乙醇析出结晶,冷却,甩滤,结晶用乙醇洗涤,干燥,得6-氨基己酸。对己内酸胺的总收率为75-80%。
用途: 止血药。对因纤维蛋白溶解活性增高而引起的某些严重出血有明显疗效。适用于多种外科手术时的渗血或局部出血。亦用于咯血、消化道出血及妇产科出血性疾患等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
768582MACKLIN6-氨基己酸用于合成103元/25g;   279元/100g;   展开
储存:2-8°C
A800336MACKLIN6-氨基己酸99%37元/25g;   89元/100g;   405元/500g;   2006元/2.5kg;   8020元/10kg;   展开
储存:2~8°C
状态:白色晶体或粉末
A793607MACKLIN6-氨基己酸10mM in Water620元/1ml;   展开
储存:-20°C
A0312TCI6-Aminohexanoic Acid>98.0%(T)210元/25G;   2250元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C6H13NO2 = 131.18
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN906872
PubChem物质ID87561965
SDBS (AIST Spectral DB)10077
Merck Index (14)432
MDL编号MFCD00008238

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Solubility in Wateralmost transparency

物性(参考值)

熔点204 ℃
水溶性完全溶解
溶解度(极微溶)甲醇
溶解性(不溶于)乙醇,乙醚,氯仿

安全信息

信号词警告
危险性说明H320 : 造成眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

相关法规

RTECS#MO6300000
A2255TCI6-Aminohexanoic Acid [for Biochemical Research]>98.0%(T)200元/5G;   440元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C6H13NO2 = 131.18
外观与形状(20℃)固体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况空气,加热
Reaxys-RN906872
PubChem物质ID87561363
SDBS (AIST Spectral DB)10077
Merck Index (14)432
MDL编号MFCD00008238

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(Nonaqueous Titration)min. 98.0 %
Solubility in Wateralmost transparency
Blotting testto pass test

物性(参考值)

熔点204 ℃

安全信息

信号词警告
危险性说明H320 : 造成眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。

相关法规

RTECS#MO6300000
259516J&K6-Aminohexanoic Acid98%920元/500G;   展开

基本信息

分子式C6H13NO2
分子量131.17
熔点207-209
MDL编码MFCD00008238
Beilstein906872
Merck14,432
EINECS 编号200-469-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSMO6300000
TSCA
145815J&K6-Aminohexanoic Acid99%89元/25g;   292元/100G;   968元/500G;   展开

基本信息

分子式C6H13NO2
分子量131.17
熔点207-209
MDL编码MFCD00008238
Beilstein906872
Merck14,432
EINECS 编号200-469-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSMO6300000
TSCA
A14719Alfa Aesar6-Aminohexanoic Acid99%551元/100g;   1495元/500g;   6232元/2500g;   展开

应用
6-Aminohexanoic acid is used as an intermediate in the polymerization of Nylon-6. It is involved in the extraction of aldehydes from the reaction mixture as well as to improve the solubilization of membrane proteins in electrophoresis. It acts as an inhibitor of fibrinolysis.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00008238

EINECS
200-469-3

分子式
C6H13NO2

分子量
131.18

熔点
210-212°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water. Slightly soluble in alcohol. Practically insoluble in ether and chloroform.

Beilstein
906872

Merck
14,432

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
MO6300000

TSCA

C10330Alfa Aesar6-Aminocaproic acid99+%1322元/100g;   3485元/500g;   16534元/2.5kg;   49135元/10kg;   展开

基本信息

Ref#
10330

MDL
8238

分子式
C6 H13 N O2

分子量
131.17

PHR1224SupelcoAminocaproic acidPharmaceutical Secondary Standard; Certified Reference Material1359.83元/1 G;   展开

产品说明

一般描述

Aminocaproic acid is a synthetic inhibitor of fibrinolysis and is utilized for the control of excessive bleeding in patients with amegakaryocytic thrombocytopenia.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Aminocaproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry and in bulk and injectable forms using colorimetric method.

生化/生理作用

赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA9036 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
EC 号200-469-3
MDL编号MFCD00008238
PubChem化学物质编号329823230
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp207-209 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur A0420000
traceable to USP 1021000
储存温度2-30℃
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
A0420000Aminocaproic acidEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
MDL编号MFCD00008238
PubChem化学物质编号329770612
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp207-209 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
07260Sigma-Aldrich6-Aminohexanoic Acid≥98.5% (NT)1635.08元/100G;   6066.01元/500G;   9801.96元/1KG;   展开

产品说明

生化/生理作用

赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

其他说明

改善膜蛋白在电泳中的溶解

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
EC 号200-469-3
MDL编号MFCD00008238
PubChem化学物质编号329748386
NACRESNA.77

产品性质

质量水平200
测定≥98.5% (NT)
mp207-209 ℃ (dec.) (lit.)
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
A2504Sigma-Aldrich6-Aminocaproic acid≥99% (titration), powder694.58元/25 G;   1382.39元/100 G;   3936.36元/500 G;   7545.69元/1 KG;   28792.6元/5 KG;   展开

产品说明

应用

EAC以25mg/ml溶解于水。因为是纤溶酶抑制剂,它被用在纤维蛋白酶分析凝血缓冲液。缓冲液是10mM磷酸钾和磷酸钠,pH6.4,再加上0.20gCaCl2, 5g 6-氨基己酸,1g叠氮化钠和9g氯化钠,都溶解在1升体系里。缓冲液在室外下无限期稳定。

包装

25, 100, 500 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

生化/生理作用

EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶,纤溶酶原激活物。
赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
EC 号200-469-3
MDL编号MFCD00008238
PubChem化学物质编号24890662
NACRESNA.77

产品性质

质量水平200
生物来源synthetic
测定≥99% (titration)
形式powder
technique(s)cell culture | mammalian: suitable
颜色 white
mp207-209 ℃ (dec.) (lit.)
溶解性H2O: 50 mg/mL
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)
rat ... Ppm1a(24666)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)404.6 - 408.2 °F
闪点(C)207 - 209 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
A7824Sigma-Aldrich6-Aminocaproic acidBioUltra, ≥99%732.41元/25 G;   1595.89元/100 G;   5506.57元/500 G;   9875.1元/1 KG;   展开

产品说明

包装

25, 100, 500 g in poly bottle
1 kg in poly bottle

生化/生理作用

赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
EC 号200-469-3
MDL编号MFCD00008238
PubChem化学物质编号24278238
NACRESNA.77

产品性质

质量水平200
生物来源synthetic (organic)
产品线BioUltra
测定≥99%
形式powder
technique(s)cell culture | mammalian: suitable
杂质≤0.005% Phosphorus (P)
≤0.1% Insoluble matter
灼烧残渣≤0.1%
mp207-209 ℃ (dec.) (lit.)
溶解性H2O: 0.5 M, clear, colorless
痕量阴离子chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
痕量阳离子Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%
储存温度room temp
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)
rat ... Ppm1a(24666)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)404.6 - 408.2 °F
闪点(C)207 - 209 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
8.00145Sigma-Aldrich6-Aminohexanoic Acidfor synthesis234.7元/5 G;   695.63元/250 G;   2299.41元/1 KG;   展开

产品说明

分析说明

含量(HClO₄): ≥ 99.0 %
鉴定(IR):通过测试

基本信息

线性分子式H2N(CH2)5COOH
分子量131.17
MDL编号MFCD00008238
EC索引号200-469-3

产品性质

质量水平200
蒸汽压<0.1 hPa ( 20 ℃)
测定≥99% (HClO4)
形式crystals
效能3400 mg/kg LD50, oral (Rat)
pH值(酸碱度)6.27-6.3 (20 ℃, 587.55 g/L in H2O)
mp205 ℃
转变温度flash point 207-209 ℃
溶解性 587.55 g/L
密度1.1313 g/cm3 at 20 ℃
储存温度2-30℃
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)404.6 - 408.2 °F
闪点(C)207 - 209 ℃
1021000USPAminocaproic acidUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

赖氨酸类似物。促进纤溶酶快速解离,从而抑制纤溶酶原的活化以及后续的纤维蛋白溶解。据报告,EACA 可抑制纤溶酶原结合至活化的血小板。早期报告表明,EACA 可抑制补体系统第一组分的活化。结合并灭活羧肽酶 B。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式H2N(CH2)5CO2H
分子量131.17
Beilstein906872
MDL编号MFCD00008238
PubChem化学物质编号329748982
NACRESNA.24

产品性质

等级pharmaceutical primary standard
形式fine crystals
powder
manufacturer/tradenameUSP
mp207-209 ℃ (dec.) (lit.)
密度1.042 g/cm3
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNCCCCCC(O)=O
InChI1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI keySLXKOJJOQWFEFD-UHFFFAOYSA-N
Gene Informationhuman ... PLAT(5327), PLG(5340)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
984544Amethyst6-Aminohexanoic Acid99%, 用于合成85元/25G;   279元/100G;   922元/500G;   3973元/2.5KG;   展开

基本信息

分子式C6H13NO2
分子量131.17
熔点207-209
MDL编码MFCD00008238
Beilstein906872
Merck14,432
EINECS 编号200-469-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSMO6300000
TSCA
103200Fluorochem6-Aminocaproic acid98%308元/25g;   440元/100g;   880元/250g;   2310元/1kg;   展开

基本信息

CAS Number60-32-2
MDL NumberMFCD00008238
Melting Point206-210℃
Density1.131

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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