| CAS: | 60-25-3 | ||||||||||||||||||
| 分子式: | C12H30Cl2N2 | ||||||||||||||||||
| 分子量: | 273.28 | ||||||||||||||||||
| 熔点: | 292°C(分解) | ||||||||||||||||||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||
| H862726 | MACKLIN | 氯化六甲二铵二水合物 | 99%(T) | 61元/1g; 189元/5g; 680元/25g; 1716元/100g; | 展开 | ||||||||||||||||||||||||||||||||||||||||
储存：室温,干燥,惰性气体存储 状态：白色固体 | |||||||||||||||||||||||||||||||||||||||||||||
| H0090 | TCI | Hexamethonium Chloride Dihydrate | >99.0%(T) | 650元/25G; 2090元/100G; 5150元/500G; | 展开 | ||||||||||||||||||||||||||||||||||||||||
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| H2138 | Sigma-Aldrich | Hexamethonium chloride | solid (hygroscopic) | 442.33元/5 G; 1272.2元/25 G; | 展开 | ||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction. 应用 Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons. 包装 5, 25 g in poly bottle 生化/生理作用 Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR. 基本信息
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