CAS 554-57-4; 醋甲唑胺; N-(4-Methyl-2-sulfamoyl-△2-1,3,4-thiadiazolin-5-ylidene)acetamide

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货号

品牌

产品名称

规格

包装、参考价格

详情

M797770

MACKLIN

醋甲唑胺

10mM in DMSO

136元/1ml;

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储存：-20°C

M857987

MACKLIN

醋甲唑胺

98%

52元/200mg; 207元/1g; 789元/5g;

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储存： 2-8°C
状态：白色到米黄色粉末

SML0720

Sigma-Aldrich

Methazolamide

≥98% (HPLC)

1589.59元/50 MG;

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产品说明

包装

50 mg in glass bottle

生化/生理作用

Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide.
Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.

其他说明

Light sensitive

基本信息

经验(实验)分子式	C₅H₈N₄O₃S₂
分子量	236.27
EC 号	209-066-7
MDL编号	MFCD00083416
PubChem化学物质编号	329825590
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	protect from light
颜色	white to beige
mp	208 ℃ (dec.) (lit.)
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
InChI	1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
InChI key	FLOSMHQXBMRNHR-QPJJXVBHSA-N
Gene Information	human ... CA1(759), CA2(760), CA4(762), CA7(766)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H351
预防措施声明	P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1406005

USP

Methazolamide

United States Pharmacopeia (USP) Reference Standard

3231.47元/500 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₅H₈N₄O₃S₂
分子量	236.27
MDL编号	MFCD00083416
PubChem化学物质编号	329750392

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
mp	208 ℃ (dec.) (lit.)
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
InChI	1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
InChI key	FLOSMHQXBMRNHR-QPJJXVBHSA-N
Gene Information	human ... CA1(759), CA2(760), CA4(762), CA7(766)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H351
预防措施声明	P201 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

494178

Fluorochem

Methazolamide

98%

704元/1g; 1936元/5g; 3300元/10g; 6886元/25g;

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基本信息

CAS Number	554-57-4
MDL Number	MFCD00083416
Melting Point	208℃

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H312: Harmful in contact with skin. H332: Harmful if inhaled. H351: Suspected of causing cancer ..
防范说明	P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P281: Use personal protective equipment as required. P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P308 + P313: IF exposed or concerned: Get medical advice/ attention. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific measures (see . on this label). P330: Rinse mouth. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to local regulations.