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CAS: 5162-03-8
分子式: C13H9ClO
分子量: 216.67
沸点: 330℃
熔点: 42-47℃
中文名称: 
2-氯苯并苯酮
2-氯二苯甲酮
邻氯二苯甲酮
邻氯二苯酮
2-氯双苯酮
英文名称: 
(2-chlorophenyl)phenylmethanone
2-chlorobenzyl phenyl ketone
2-chloro-benzophenon
(2-chlorophenyl)phenyl-methanon
o-chlorobenzophenone
2-Chloro diphenyl ketone
(2-Chlorophenyl)phenyl methanone
2-Chlorobenzophenone
性质描述: 片状结晶。熔点52-56℃,沸点330℃,185-188℃(1.73kPa)。
生产方法: 由邻氯苯甲酸经氯化、缩合而得。在反应锅内加入邻氯苯甲酸和苯,搅拌升温至50-70℃,慢慢加入氯化亚砜。加毕,升温至80℃回流5h,氯化得邻氯苯甲酰氯。将此氯化液加入温度为10-20℃含三氯化铝的苯中,在20-25℃下反应5h。反应毕,倾入冰水中水解,加入盐酸,分取苯层,用10%氢氧化钠溶液洗涤,水洗涤,蒸除苯和水至尽得2-氯双苯酮。
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C804296MACKLIN2-氯二苯甲酮99%30元/5g;   40元/25g;   72元/100g;   315元/500g;   1234元/2.5kg;   4650元/10kg;   展开
储存:室温
状态:无色液体
C1150TCI2-Chlorobenzophenone>98.0%(GC)290元/25G;   690元/100G;   2490元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C13H9ClO = 216.66
外观与形状(20℃)固体
Reaxys-RN1869594
PubChem物质ID87566179
SDBS (AIST Spectral DB)15180
MDL编号MFCD00000558

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 98.0 %
Melting point44.0 to 48.0 ℃

物性(参考值)

熔点46 ℃
沸点180 ℃/15 mmHg

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#PC4945633
138573J&K2-Chlorobenzophenone97%60元/5G;   120元/25G;   355元/100G;   展开

基本信息

分子式C13H9ClO
分子量216.66
熔点44-47
沸点330
闪点>113
MDL编码MFCD00000558
Beilstein1869594
EINECS 编号225-936-9

安全信息

防范说明P262
WGK3
RTECSPC4945633
TSCA
A15867Alfa Aesar2-Chlorobenzophenone99+%891元/25g;   2649元/100g;   10578元/500g;   展开

基本信息

MDL
MFCD00000558

EINECS
225-936-9

分子式
C13H9ClO

分子量
216.67

熔点
44-47°

沸点
330°

闪点
>110°(230°F)

形态
Crystalline powder/lumps

Beilstein
1869594

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

194387Sigma-Aldrich2-Chlorobenzophenone≥99%438.03元/25 G;   展开

产品说明

一般描述

Thermodynamics of formation of inclusion complex between 2-chlorobenzophenone and cyclomaltoheptaose (β-cyclodextrin) has been investigated by UV-vis spectroscopy and reversed-phase liquid chromatography. 2-Chlorobenzophenone undergoes reduction in the presence of LiAlH4 and (R)-(-)-2-(2-iso-indolinyl)butan-1-ol to afford the corresponding benzhydrols.

应用

2-Chlorobenzophenone was used in the synthesis of 1-(2-chlorophenyl)isoquinolin-3-yl trifluoromethanesulfonate.

包装

25 g in poly bottle

基本信息

线性分子式ClC6H4COC6H5
分子量216.66
EC 号225-936-9
MDL编号MFCD00000558
PubChem化学物质编号24851648
NACRESNA.22

产品性质

质量水平100
测定≥99%
bp330 ℃ (lit.)
mp44-47 ℃ (lit.)
SMILES stringClc1ccccc1C(=O)c2ccccc2
InChI1S/C13H9ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H
InChI keyVMHYWKBKHMYRNF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
Y0000818Clotrimazole impurity EEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式ClC6H4COC6H5
分子量216.66
MDL编号MFCD00000558
PubChem化学物质编号329831167
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
bp330 ℃ (lit.)
mp44-47 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringClc1ccccc1C(=O)c2ccccc2
InChI1S/C13H9ClO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H
InChI keyVMHYWKBKHMYRNF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
238831Fluorochem(2-Chlorophenyl)(phenyl)methanone98%220元/1g;   264元/25g;   902元/100g;   3850元/500g;   展开

基本信息

CAS Number5162-03-8
MDL NumberMFCD00000558
Boiling Point180℃/15mmHg(lit.)
Melting Point44-48℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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