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CAS: 512-04-9
分子式: C27H42O3
分子量: 414.62
熔点: 205-208°C
中文名称: 
薯蓣皂苷元
(25R)-螺甾-5-烯-3β-醇
薯芋皂素
(3β,25R)-螺甾-5-烯-3-醇
薯蓣皂素
地奥配质
薯蓣皂苷配基
薯芋皂苷配基
英文名称: 
Spirost-5-en-3-ol,(3.beta.,25R)-
(25R)-Spirost-5-en-3-ol
5-25D-Spirosten-3-ol
5-22-Spirosten-3-ol
20F,22F-Spirosten-3-ol
(3.beta.,25R)-Spirost-5-en-3-ol
Diosgenin
Nitrogenin
(25R)-spirost-5-en-3-beta-o
nitogenin
(3-beta,25R)-spirost-5-en-3-o
展开更多英文名
性质描述: 片状或针状结晶。熔点204-207℃。易溶于汽油、乙醇,氯仿等有机溶剂,不溶于水。
生产方法: 以川地龙生药或黄姜为原料,经水解、提取而得。
用途: 本品是重要的甾族皂苷元,是半合成甾族化合物的重要原料。将薯蓣皂素进行开环、氧化、水解和消除反应,可制得孕甾双烯酮醇。再经肟化、重排和水解,可制得去氢表雄酮。这些中间体在药物生产中有重要价值。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D806406MACKLIN薯蓣皂素分析对照品108元/20mg;   210元/100mg;   展开
储存:2~8°C
状态:白色到浅黄色粉末
D806408MACKLIN薯蓣皂素95%35元/1g;   65元/5g;   176元/25g;   581元/100g;   1927元/500g;   展开
储存:2~8°C
状态:白色或浅黄色粉末
D806407MACKLIN薯蓣皂素90%30元/1g;   61元/5g;   169元/25g;   496元/100g;   展开
储存:2~8°C
状态:白色到微黄色固体
D1474TCIDiosgenin>95.0%(GC)185元/1G;   620元/10G;   展开

基本信息

纯度/分析方法>95.0%(GC)
分子式/分子量C27H42O3 = 414.63
外观与形状(20℃)固体
PubChem物质ID87567972
SDBS (AIST Spectral DB)11108
Merck Index (14)3295
MDL编号MFCD00016887

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 95.0 %
Melting point205.0 to 208.0 ℃
Specific rotation [a]20/D-123 to -127 deg(C=1, CHCL3)

物性(参考值)

熔点205 ℃
比旋光度 [α]D-126° (C=1,CHCl3)

相关法规

RTECS#WH1450000
929480J&KDiosgenin98%209元/1G;   展开

基本信息

分子式C27H42O3
分子量414.63
MDL编码MFCD00016887
Beilstein94582
Merck14,3295
EINECS 编号208-134-3

安全信息

防范说明P262
WGK2
RTECSWH1450000
TSCA
916900J&KDiosgenin, for identification, from Dioscoreae nipponicae rhizoma, NIFDC traceable用于鉴别, 来源于穿山龙, 可溯源至中检院标准品69元/20MG;   展开

基本信息

分子式C27H42O3
分子量414.63
MDL编码MFCD00016887
983766J&KDiosgenin来源于穿山龙, 有效含量≥90%, 可溯源至中检院标准品910元/20MG;   展开

基本信息

分子式C27H42O3
分子量414.63
MDL编码MFCD00016887
D1634Sigma-AldrichDiosgenin≥93%802.97元/5 G;   7101.2元/100 G;   展开

产品说明

一般描述

薯蓣皂苷元是一种三萜类化合物,也是薯蓣皂苷的糖基衍生物。 它存在于山药、胡芦巴(Trigonella foenum-graecum)和闭鞘姜(Costus speciosus)等植物中。

应用

薯蓣皂苷元已被用于:

  • 作为分析毛瓣无患子所含总皂苷的标准品
  • 口服给予大鼠,以研究其对致动脉粥样化饮食诱导的心脏、肝脏和大脑炎症介质产生的抵抗作用
  • 作为标准化合物,用于检测鹰嘴豆和蒺藜的皂苷含量

包装

5, 100 g in poly bottle

生化/生理作用

薯蓣皂苷元能诱导结肠癌细胞凋亡以及诱导骨肉瘤细胞的凋亡、细胞周期停滞和环加氧酶活性。它是类固醇药物生产的前体。薯蓣皂苷元已被证明能够通过刺激胆汁排泄来促进胆固醇生成。它能够影响脂氧合酶诱导的人红白血病细胞系分化。

基本信息

经验(实验)分子式C27H42O3
分子量414.62
Beilstein94582
EC 号208-134-3
MDL编号MFCD00016887
PubChem化学物质编号24893501
NACRESNA.77

产品性质

质量水平200
测定≥93%
SMILES string[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]6(CC[C@@H](C)CO6)O2
InChI1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChI keyWQLVFSAGQJTQCK-VKROHFNGSA-N
Gene Informationhuman ... UGT1A4(54657)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
700085PAvantiDiosgeninAvanti Polar Lipids487.58元/100 mg;   展开

产品说明

一般描述

Diosgenin is a steroid precursor derived from saponins extracted from the tubers of wild yams.
Diosgenin is a steroidal sapogenin, which is produced by the hydrolysis of the saponin dioscin. It is extracted from Dioscorea, Trigonella, Costus and Smilax species.

生化/生理作用

Diosgenin exhibits anti-inflammatory, anticancer, antimetastatic and antioxidant activities. It also exerts anticoagulant and antithrombotic properties. Diosgenin is used to treat cerebral disorders, allergic diseases and diabetes. It possesses anti-infectious against fungi, bacteria, protozoa and virus.

包装

5 mL Amber Glass Screw Cap Vial (700085P-100mg)

基本信息

经验(实验)分子式C27H42O3
分子量414.62
NACRESNA.25

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 100 mg (700085P-100mg)
manufacturer/tradenameAvanti Polar Lipids 700085P
运输dry ice
储存温度−20℃
SMILES stringC[C@@]12C(C[C@H]3[C@@H]2[C@H](C)[C@]4(OC[C@H](C)CC4)O3)C5CC=C6C[C@@H](O)CC[C@]6(C)C5CC1
InChI1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChI keyWQLVFSAGQJTQCK-VKROHFNGSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
Y0001871DiosgeninEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C27H42O3
分子量414.62
Beilstein94582
MDL编号MFCD00016887
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
格式neat
储存温度2-8℃
SMILES string[H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]6(CC[C@@H](C)CO6)O2
InChI1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
InChI keyWQLVFSAGQJTQCK-VKROHFNGSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
012718FluorochemDiosgenin97%220元/5g;   220元/1g;   550元/25g;   1232元/100g;   展开

基本信息

CAS Number512-04-9
MDL NumberMFCD00016887
Melting Point203-207℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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