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关键词:       仅模糊查询
CAS: 50-33-9
分子式: C19H20N2O2
分子量: 308.37
中文名称: 
保泰松
4-丁基-1,2-二苯基-3,5-吡咯烷二酮
布他酮
布他唑立丁
布泰其安
苯丁唑啉
英文名称: 
benzone
betazed
bizolin
bizolin 200
bunetzone
butacompren
butacote
butadion
butalidon
butapirazol
butartrina
butazina
butazolidin
butazolidine
butidiona
butiwas-simple
butoz
buvetzone
buzon
chembutazone
da-192
digibutina
diossidone
diozol
diphebuzol
diphenylbutazone
ecobutazone
elmedal
equi bute
equipalazone
eributazone
exrheudon n
febuzina
fenartil
fenibutal
fenibutasan
fenibutazona
fenibutol
fenilbutazona
fenilbutina
fenilbutine
fenilidina
fenotone
fenylbutazon
flexazone
g 13,871
g 13871
ia-but
intrabutazone
intrazone
mephabutazon
mephabutazone
nc1-c56531
nci-c56531
neo-zoline
phebuzine
phenyl-mobuzon
phenylbutazon
phenylbutazone
phenyzone
pirarreumol "b"
pirarreumol b
praecirheumin
pyrabutol
r-3-zon
rectofasa
reudo
reudox
reumazin
reumuzol
reupolar
robizone
robizone-v
rubatone
scanbutazone
schemergen
schemergin
shigrodin
spondyril
tencodyne
tevcodyne
ticinil
todalgil
usaf ge-15
uzone
vac-10
zolaphen
4-Butyl-1,2-diphenyl-pyrazolidine-3,5-dione
Phenylbutzone
1,2-diphenyl-2,3-dioxo-4-n-butylpyrazoline
1,2-diphenyl-3,5-dioxo-4-butylpyrazolidine
1,2-diphenyl-4-butyl-3,5-dioxopyrazolidine
1,2-diphenyl-4-butyl-3,5-pyrazolidinedione
3,5-dioxe-4 buty-1, diphenyl-pyrazolidine
3,5-dioxo-1,2-diphenyl-4-n-butyl-pyrazolidin
3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidine
3,5-dioxo01,2-diphenyl-4-m-butyl-pyrazolidine
4-butyl-1,2-diphenyl-5-pyrazolidinedione
4-butyl-1,2-diphenyl-3,5-dioxopyrazolidine
4-butyl-1,2-diphenyl-3,5-pyrazolidinedione
4-butyl-1,2-diphenylpyrazolidine-3,5-dione
4-n-butyl-1,2-diphenyl-3,5-pyrazolidinedione
alindor
alkabutazona
alqoverin
antadol
anuspiramin
arthrizon
artrizin
artrizone
artropan
azolid
展开更多英文名
性质描述: 白色或类白色结晶性粉末。熔点105.5-106.5℃。易溶于丙酮、氯仿或苯，溶于乙醇或乙醚，几乎不溶于水，溶于氢氧化钠溶液。无臭，味略苦。
生产方法: 由氢化偶氮苯与丁基丙二酸二乙酯环合而得。将氢化偶氮苯、丁基丙二酸二乙酯、甲醇钠和亚硫酸钠一起加热，剧烈回流1.5h，生在保泰松钠盐，再用乙酸酸化得到保泰松。
用途: 该品具有解热镇痛、抗炎及抗风湿作用，主要用于治疗风湿性、类风湿性关节炎及痛风。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P797875MACKLIN保泰松10mM in DMSO468元/1ml;   展开
储存：-20°C
P1686TCIPhenylbutazone>98.0%(T)(HPLC)290元/25G;   990元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C19H20N2O2 = 308.38
外观与形状(20℃)固体
Reaxys-RN290080
PubChem物质ID87558949
Merck Index (14)7277
MDL编号MFCD00005500

技术规格

AppearanceWhite to Yellow to Orange powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point104.0 to 108.0 ℃

物性(参考值)

熔点106 ℃
水溶性不溶
在水中的溶解度0.2 g/l   25 ℃
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词危险
危险性说明H301 : 吞咽会中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P310 + P330 : 如误吞咽：立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#UQ8225000

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
451567J&KPhenylbutazone99%82元/5G;   181元/25G;   596元/100G;   展开

基本信息

分子式C19H20N2O2
分子量308.38
熔点106-108
MDL编码MFCD00005500
Beilstein290080
Merck14,7277
EINECS 编号200-029-0

安全信息

图形或危害标志
提示语Danger
危险说明H301
H312
H315
H319
H332
H335
防范说明P261
P280
P301+P310
P305+P351+P338
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSUQ8225000
TSCA是
L03449Alfa AesarPhenylbutazone98%796元/25g;   2170元/100g;   展开

应用
A non-steroidal anti-inflammatory drug

基本信息

MDL
MFCD00005500

EINECS
200-029-0

分子式
C19H20N2O2

分子量
308.38

熔点
105-108°

灵敏度
Ambient temperatures.

形态
Powder

Beilstein
290080

Merck
14,7277

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H319-H351-H361
Toxic if swallowed.Causes serious eye irritation.Suspected of causing cancer.Suspected of damaging fertility or the unborn child.

Precautionary Statements
P280h-P305+P351+P338-P309-P310
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.

安全信息

危险等级
6.1

包装组
III

危险类别
22-36-40-63
Harmful if swallowed.Irritating to eyes.Limited evidence of a carcinogenic effect.Possible risk of harm to the unborn child.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
UQ8225000

TSCA
是

C19931Alfa AesarPhenylbutazone99+%798元/5g;   展开

基本信息

Ref#
19931

MDL
5500

分子式
C19 H20 N2 O2

分子量
308.38

安全信息

危险等级
6.1

包装组
III

P1200000PhenylbutazoneEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
MDL编号MFCD00005500
PubChem化学物质编号329820078
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp106-108 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P8386Sigma-AldrichPhenylbutazone1142.25元/25 G;   1726.73元/100 G;   5094.27元/500 G;   展开

产品说明

应用

保泰松已被用于：

  • 在转基因斑马鱼(LiPan)肝毒素测定中用作肝毒素
  • 在高效液相色谱-紫外(HPLC-UV)中用作标准品
  • 在鸡′蛋绒毛尿囊膜试验(HET-CAM试验)中用作抗炎化合物

包装

25, 100, 500 g in poly bottle

生化/生理作用

保泰松是一种肝毒素，可与血浆蛋白结合。它可用于治疗马的炎症。保泰松具有治疗强直性脊柱炎的潜力。它可通过诱导肌盲样蛋白1(MBNL1)的表达而具有治疗I型强直性肌营养不良(DM1)的潜力。它还有利于骨骼肌中肌肉氯离子通道的表达。

底物

非甾体抗炎化合物；环氧合酶抑制剂，也是环氧合酶过氧化的底物。

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
EC 号200-029-0
MDL编号MFCD00005500
PubChem化学物质编号24277729
NACRESNA.77

产品性质

质量水平200
生物来源synthetic (organic)
测定≥98% (HPLC)
形式powder
mp106-108 ℃ (lit.)
溶解性ethanol: 50 mg/mL, clear, colorless to light yellow
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N
Gene Informationhuman ... CYP2C9(1559), PTGIS(5740), PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
79184SupelcoPhenylbutazoneanalytical standard850.95元/50 MG;   展开

产品说明

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
EC 号200-029-0
MDL编号MFCD00005500
PubChem化学物质编号329768297
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥98.5% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
杂质≤0.5% water
mp106-108 ℃ (lit.)
application(s)forensics and toxicology
veterinary
格式neat
储存温度15-25℃
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1531007USPPhenylbutazoneUnited States Pharmacopeia (USP) Reference Standard3231.47元/250 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
MDL编号MFCD00005500
PubChem化学物质编号329750815
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp106-108 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
80184SupelcoPhenylbutazonecertified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland1045.7元/100 mg;   展开

产品说明

一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

TraceCERT is a registered trademark of sigma-aldrich Co. LLC

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
EC 号200-029-0
MDL编号MFCD00005500
PubChem化学物质编号329768727
NACRESNA.24

产品性质

质量水平300
等级certified reference material
TraceCERT®
产品线TraceCERT®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp106-108 ℃ (lit.)
application(s)cleaning products
cosmetics
food and beverages
personal care
格式neat
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR2607SupelcoPhenylbutazonepharmaceutical secondary standard, certified reference material1987.23元/500 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C19H20N2O2
分子量308.37
MDL编号MFCD00005500

产品性质

等级certified reference material
pharmaceutical secondary standard
形式powder
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp106-108 ℃ (lit.)
药典可追溯性traceable to PhEur P1200000
traceable to USP 1531007
储存温度2-30℃
SMILES stringCCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3
InChI1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
InChI keyVYMDGNCVAMGZFE-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语：Danger
危险声明H301 - H312 + H332 - H315 - H319 - H335
预防措施声明P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
358148Fluorochem4-Butyl-1,2-diphenylpyrazolidine-3,5-dione95%462元/25g;   1782元/100g;   4884元/500g;   展开

基本信息

CAS Number50-33-9
MDL NumberMFCD00005500
Melting Point106℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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