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CAS: 464-45-9
分子式: C10H18O
分子量: 154.24
沸点: 210℃
熔点: 204-208℃
中文名称: 
(-)-合成龙脑
2-莰醇
(1S)-(-)-冰片
合成右旋龙脑
龙脑
莰醇-[2]
英文名称: 
1,7,7-trimethyl-, (1S-endo)-Bicyclo[2.2.1]heptan-2-ol
7,7-trimethyl- (1S-endo)-bicyclo(2.2.1)heptan-2-o
(-)-borneol
1-bornyl alcohol
7,7-trimethyl- (1S-endo)-bicyclo[2.2.1]heptan-2-o
(1S,2R,4S)-(-)-borneo
l-2-bornanol
l-2-camphanol
l-borneol
linderol
ngai camphor
l(-)-borneol
endo-2-Hy-droxy camphane
Bornen camphor
Malayan cam-phor
synthetic d-borneol
endo-(1S)-1,7,7-Trimethylbicyclo[2,2,1]heptan-2-ol
[(1S)-endo]-(-)-Borneol
Bicyclo[2.2.1]heptan-2-ol,1,7,7-trimethyl-,(1S-endo)-
展开更多英文名
性质描述: 白色半透明结晶。有似樟脑气味,能溶于醇和醚,微溶于水。具挥发性和升华性。该品有旋光异构现象。以前,由于是从天然樟脑制得,一般是d-冰片。而最近主要由合成樟脑制造,dl-冰片占了大部分。d-冰片为六面片状结晶。熔点208℃,沸点212℃。有一种特殊的辣椒气味,并具有类似薄荷的味道。能升华,担挥发性比樟脑小。几乎不溶于水,176份d-冰片可溶于100份无水乙醇中(w/W),深于醚、石油醚(1:6)、苯(1:5)、甲苯、丙酮、十氢化萘及四氢化萘。l-冰片熔点204℃,沸点210℃。dl冰片熔点206-207℃。
生产方法: 将樟脑溶于乙醇中,用金属钠还原、或以镍、铜等作催化剂,在常压或加压下将樟脑还原,以松节油为原料,分馏得到蒎烯馏分,将蒎烯与草酸催化异构并加成生成草酸龙脑酯,加苛性钠溶液水解,使冰片游离,用水蒸气馏分离出冰片。以蒎烯为原料生产冰片的另一种工艺过程是:在蒎烯中通入干燥HCI,得冰片基氯,将其干燥并溶于乙醚,加入镁粉,反应到镁粉消失,接着通入氧气。吸收氧气之后,用硫酸分解。生成物含冰片65-85%、异冰片5-8%。
用途: 广泛用于配制迷迭香、薰衣草型等香精,在牙膏、爽身粉以及其他化妆品中应用颇多,用作肥皂、溶剂及室内喷雾剂和中国墨的加香剂。也是宗教(印度教)上用的薰香香料。冰片性微寒,味辛苦,有通窍、散郁火、止痛退翳之功能,故在中药用于中风、惊痫、喉痹齿痛、口疮痈疡等,多入丸散剂。常见的不良反应有恶心、呕吐、精神混乱、眩晕、痉挛等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
B803312MACKLIN合成左旋龙脑98%73元/5g;   196元/25g;   618元/100g;   展开
储存:室温,易燃物区域
状态:白色到灰白色粉末或晶体
折射率:-36 ° (C=5, EtOH)
L794128MACKLIN合成左旋龙脑10mM in DMSO125元/1ml;   展开
储存:-20°C
B1012TCI(-)-Borneol>95.0%(GC)265元/25G;   1830元/500G;   展开

基本信息

纯度/分析方法>95.0%(GC)
分子式/分子量C10H18O = 154.25
外观与形状(20℃)固体
Reaxys-RN2322962
PubChem物质ID87563964
SDBS (AIST Spectral DB)6801
Merck Index (14)1338
MDL编号MFCD00003759

技术规格

AppearanceWhite to Almost white powder to crystaline
Purity(GC)min. 95.0 %
Specific rotation [a]20/D-33.0 to -40.0 deg(C=5, EtOH)
Solubility in EtOHalmost transparency

物性(参考值)

熔点207 ℃
比旋光度 [α]D-36° (C=5,EtOH)

安全信息

图形或危害标志
信号词警告
危险性说明H316 : 造成轻微皮肤刺激。
H402 : 对水生生物有害。
H228 : 易燃固体。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P240 : 容器和装载设备接地/等势联接。
P210 : 远离热源/火花/明火/热表面。禁止吸烟。
P241 : 使用防爆的电气/通风/照明设备。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P370 + P378 : 火灾时:使用干砂、干粉或抗醇泡沫灭火。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#DT5095000

运输信息

UN编号UN1312
类别4.1
包装类别 III
监管条件代码(*)
A12684Alfa Aesar(-)-Borneol97+%476元/50g;   1110元/250g;   3554元/1000g;   展开

应用
(-)-Borneol is used to prepare its esters by reacting with acids. Its derivatives are used as chiral ligands in asymmetric synthesis. It is also used in flavors and perfumes. Further, it is used in traditional Chinese medicine as moxa. In addition to this, it is used as a component of many essential oils and also used as a natural insect repellent.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00003759

EINECS
207-353-1

分子式
C10H18O

分子量
154.25

熔点
208-211°

沸点
210°

闪点
65°(149°F)

灵敏度
Ambient temperatures.

形态
Crystalline solid

溶解性
Soluble in chloroform, ethanol, acetone, ether, benzene, toluene, decalin and tetralin. Insoluble in water.

Beilstein
3587558

Merck
14,1338

GHS危害和防范说明

GHS符号

Hazard Statements
H228
Flammable solid.

Precautionary Statements
P210-P280-P240-P241-P370+P378a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Wear protective gloves/protective clothing/eye protection/face protection.Ground/bond container and receiving equipment.Use explosion-proof electrical/ventilating/lighting/ equipment.In case of fire: Use for extinction: CO2, powder or water spray.

安全信息

UN#
UN1312

危险等级
4.1

包装组
III

危险类别
11
Highly flammable.

安全等级
33
Take precautionary measures against static discharges.

欧盟危险品标志

RTECS
DT5095000

TSCA

C16065Alfa AesarL(-)-Borneol97%605元/25g;   910元/100g;   4400元/500g;   展开

基本信息

Ref#
16065

MDL
3759

分子式
C10 H18 O

分子量
154.25

闪点
65

形态
White cryst solid

安全信息

危险等级
4.1

包装组
III

15598Supelco(-)-Borneolanalytical standard661.92元/1 G;   展开

产品说明

一般描述

(-)-冰片烯是对映体。它是一种双环单萜化合物,通常用于镇痛和麻醉。它被认为是GABA受体的正调节剂。

应用

关于适当的仪器技术的更多信息,请参见产品的检验报告。联系技术服务部寻求进一步支持。

基本信息

经验(实验)分子式C10H18O
分子量154.25
Beilstein2038053
EC 号207-353-1
MDL编号MFCD00003759
PubChem化学物质编号329750939
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥99.0% (sum of enantiomers, GC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)food and beverages
格式neat
SMILES stringCC1(C)[C@H]2CC[C@]1(C)[C@H](O)C2
InChI1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1
InChI keyDTGKSKDOIYIVQL-QXFUBDJGSA-N

安全信息

象形图GHS02
警示用语:Warning
危险声明H228
预防措施声明P210 - P240 - P241 - P280 - P370 + P378
危险分类Flam. Sol. 2
储存分类代码4.1B - Flammable solid hazardous materials
WGKWGK 2
闪点(F)150.8 °F
闪点(C)66 ℃
个人防护装备Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
8.14472Sigma-Aldrich(1S)-(-)-Borneolfor synthesis410.52元/25 G;   655.03元/100 G;   1230.28元/250 G;   展开

产品说明

分析说明

Assay (GC, area%): ≥ 96.0 % (a/a)
Spec. rotation [α²0/D (c=5 in ethanol): -37.0 - -34.0 °
Identity (IR): passes test

基本信息

经验(实验)分子式C10H18O
分子量154.25
MDL编号MFCD00003759
EC索引号207-353-1

产品性质

质量水平200
测定≥96.0% (GC)
效能5800 mg/kg LD50, oral (Rat)
mp205-208 ℃
转变温度flash point 66 ℃
储存温度2-30℃
InChI1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8-,10-/m1/s1
InChI keyDTGKSKDOIYIVQL-NQMVMOMDSA-N

安全信息

象形图GHS02
警示用语:Warning
危险声明H228
预防措施声明P210 - P240 - P241 - P280 - P370 + P378
危险分类Flam. Sol. 2
储存分类代码4.1B - Flammable solid hazardous materials
WGKWGK 2
闪点(F)150.8 °F
闪点(C)66 ℃
PHR2429SupelcoD-Camphor Impurity J, endo-borneolPharmaceutical Secondary Standard; Certified Reference Material6146.58元/100 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC4530 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C10H18O
分子量154.25
Beilstein2038053
MDL编号MFCD00003759

产品性质

等级certified reference material
pharmaceutical secondary standard
形式powder
包装pkg of 100 mg
储存温度2-30℃
SMILES stringCC1(C)[C@H]2CC[C@]1(C)[C@H](O)C2
InChI1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m0/s1
InChI keyDTGKSKDOIYIVQL-QXFUBDJGSA-N

安全信息

象形图GHS02
警示用语:Warning
危险声明H228
预防措施声明P210
危险分类Flam. Sol. 2
储存分类代码4.1B - Flammable solid hazardous materials
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
CP-TER-003SAccuStandard(-)-Borneol Standard,100 μg/mL in Methanol100 μg/mL in Methanol309元/1mL;   展开
(-)-Borneol(-)-冰片464-45-9100 µg/mL
358040Fluorochem(1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol97%418元/1g;   1188元/5g;   展开

基本信息

CAS Number464-45-9
MDL NumberMFCD00003759
Boiling Point210℃
Melting Point206-209℃

安全信息

图形或危害标志
危险性说明 H228: Flammable solid.
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H317: May cause an allergic skin reaction.
H332: Harmful if inhaled.
H412: Harmful to aquatic life with long lasting effects.
防范说明 P210: Keep away from – No smoking.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof ./ equipment.
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P272: Contaminated work clothing should not be allowed out of the workplace.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P333 + P313: If skin irritation or rash occurs: Get medical advice/attention.
P363: Wash contaminated clothing before reuse.
P370 + P378: In case of fire: Use CO2, foam or extinguishing powder for extinction.
P501: Dispose of contents/container to local regulations.
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