| CAS: | 436133-68-5 | ||
| 分子式: | C15H11ClF3N5O4S | ||
| 分子量: | 449.79 | ||
| 英文名称: |
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| 用途: | Kobe0065 是一种新颖的，有效的 Ras-Raf 相互作用抑制剂，能够完全抑制 H-Ras·GTP 与 c-Raf-1 RBD 的结合，Ki 值为 46±13 μM。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||
| K794027 | MACKLIN | Kobe0065 | 10mM in DMSO | 496元/1ml; | 展开 | ||||||||||||||||||||||||||||||||||
储存：-20°C, 避光, 惰性气体 | |||||||||||||||||||||||||||||||||||||||
| K860899 | MACKLIN | Kobe0065 | ≥98% | 304元/5mg; 397元/10mg; 1343元/50mg; | 展开 | ||||||||||||||||||||||||||||||||||
储存：-20℃ 状态：黄色粉末 折射率：light yellow solid | |||||||||||||||||||||||||||||||||||||||
| SML0961 | Sigma-Aldrich | Kobe0065 | ≥98% (HPLC) | 1117.23元/5 MG; | 展开 | ||||||||||||||||||||||||||||||||||
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 Kobe0065 binds to Ras-GTP, blocking interactions with Raf kinase. Kobe0065 inhibits anchorage-dependent and -independent growth, blocks MEK/ERK activity and induces apoptosis in H-rasG12V transformed NIH3T3 cells. The compound Kobe0065 also inhibts tumor growth in SW480 colon cancer cell xenografts. 特点和优势 This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. 基本信息
产品性质
安全信息
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