| CAS: | 288150-92-5 | |
| 分子式: | C19H18F2N4O | |
| 分子量: | 356.37 | |
| 中文名称: |
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| 英文名称: |
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| 用途: | SB408124是一种非肽类OX1 receptor拮抗剂，作用于全细胞和膜，Ki分别为57 nM和27 nM，比作用于OX2受体选择性高50倍。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S872354 | MACKLIN | SB408124 | 95% | 1248元/25mg; 3200元/100mg; 4800元/250mg; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
储存：-20℃ 状态：粉末 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S2694 | Sigma-Aldrich | SB-408124 | ≥98% (HPLC), solid | 1943元/5 MG; 6673.28元/25 MG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 应用 SB-408124 was used to block orexin A-mediated cardiovascular effects in rats. It was used to study block the increase of endogenous glucose production mediated by bicuculline in rats. 包装 5, 25 mg in glass bottle 生化/生理作用 SB-408124 blocks the orexin type 1 receptor that stimulates the production of stress hormone in hypothalamus. It blocks orexin A-induced increase in arterial pressure and elevation of heart rate in rats. SB-408124 modulates phrenic nerve activity that is important in respiration. 特点和优势 This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. 法律信息 Sold for research purposes under agreement from GlaxoSmithKline 基本信息
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