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CAS: 2624-44-4
分子式: C10H17NO5S
分子量: 263.33
熔点: 125℃
中文名称: 
酚磺乙胺
止血敏
止血定
氢酯磺乙酸
2,5-二羟基苯磺酸二乙胺盐
英文名称: 
2,5-dihydroxy-benzenesulfonic aci compd. with diethylamine
1-hydroxy-4-oxo-2,5-cyclohexadiene-1-sulfonic acid compd. with diethylamine
2,5-dihydroxybenzenesulfonic acid compd. with n-ethylethanamine
aglumin
altodor
2,5-dihydroxy-benzenesulfonic aci compd. with n-ethylethanamine (1:1)
ciclonamina
cyclonamine
dicynene
dicynone
diethylammonium 2,5-dihydroxybenzenesulfonate
diethylammonium cyclohexadien-4-ol-1-one-4-sulfonate
diidroxi-1,4-benzenesulfonato-3-di-etilammonium
e 141
eselin
etamsylate
ethamsylate
md 141
2,5-Dihydroxybenzenesulfonic acid compd with N-ethylethanamine
Cyclon-amine
展开更多英文名
性质描述: 白色结晶性粉末。熔点125℃(127-131℃)。易溶于水,溶于乙醇,微溶于丙酮,不溶于氯仿、乙醚。有引湿性,遇光易变质。无臭,味苦。
生产方法: 由二乙胺用二氧化硫成盐后与对苯二醌加成而得。将二乙胺、乙醇和水加入反应锅内,冷至0℃,通入二氧化硫至反应液pH=3.5-4为止,反应温度控制在10℃以下,得二乙胺亚硫酸盐溶液。然后,于0-10℃缓缓加入对苯二醌。加毕,减压回收乙醇,冷却结晶,过滤。结晶加蒸馏水加热溶解,用活性炭脱色精制,即得酚磺乙胺成品。
用途: 本品能增加血小板的数量、聚集性和粘附性,促使凝血活性物质从血小板中释放。也可加速血块收缩,缩短凝血时间,还可以增强毛细血管抵抗力,减低毛细血管通透性。用于手术前预防和治疗出血。也用于血小板功能不全引起出血或其他原因出血,如胃肠道出血、脑出血和泌尿道出血等。鼠静脉注射LD50为800-1350毫克/公斤。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
E797757MACKLIN酚磺乙胺10mM in DMSO150元/1ml;   展开
储存:-20°C
E822879MACKLIN酚磺乙胺99%28元/1g;   33元/5g;   43元/25g;   126元/100g;   420元/500g;   1680元/2.5kg;   展开
储存:2~8 ℃
状态:白色晶体或结晶粉末
E1145TCIEtamsylate>98.0%(T)(HPLC)590元/1G;   1400元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C10H17NO5S = 263.31
外观与形状(20℃)固体
相关CAS RN88-46-0
Reaxys-RN4166074
PubChem物质ID253660744
Merck Index (14)3722
MDL编号MFCD00867499

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point128.0 to 132.0 ℃

物性(参考值)

熔点130 ℃
水溶性可溶

相关法规

RTECS#DB6145000
E1830000EtamsylateEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C10H17NO5S
分子量263.31
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
InChI keyHBGOLJKPSFNJSD-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
SML2508Sigma-AldrichEtamsylate1275.67元/50 MG;   展开

产品说明

生化/生理作用

Etamsylate (or ethamsylate) is a haemostatic agent; also promotes angioprotective and proaggregant action. It stimulates thrombopoiesis and their release from bone marrow. Haemostatic action is due to activation of thromboplastin formation on damaged sites of small blood vessels and decrease of PgI2 (Prostacyclin I2) synthesis; it also facilitates platelet aggregation and adhesion, that at last induce decrease and stop of hemorrhage.

基本信息

经验(实验)分子式C10H17NO5S
分子量263.31

产品性质

形式powder
储存温度2-8℃
InChI1S/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
InChI keyHBGOLJKPSFNJSD-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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