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CAS: 2516-96-3
分子式: C7H4ClNO4
分子量: 201.56
熔点: 164-168℃
中文名称: 
2-氯-5-硝基苯甲酸
英文名称: 
Benzoic acid,2-chloro-5-nitro-
2-chloro-5-nitro-benzoic aci
2-chloro-5-nitrobenzoic acid
性质描述: 从水中析出针状结晶。熔点165-166℃(166-168℃),相对密度1.608(18/4℃)。溶于乙醇、乙醚、苯,微溶于冷水。
生产方法: 由邻氯苯甲酸经硝化而得。将邻氯苯甲酸、硫酸冷却至0℃以下,然后加混酸,在0℃下进行硝化,反应8h后,加热至60℃,再倒入冰水中析出硝基物,再结晶即得成品。
用途: 用于合成2-氯-5-氨基苯甲酸、5-硝基水杨酸及其酯类、酰胺类中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C804279MACKLIN2-氯-5-硝基苯甲酸99%30元/25g;   58元/100g;   288元/500g;   571元/1kg;   1427元/2.5kg;   2699元/5kg;   展开
储存:室温
状态:白色到灰白色粉末
C0877TCI2-Chloro-5-nitrobenzoic Acid>98.0%(GC)(T)200元/25G;   1370元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C7H4ClNO4 = 201.56
外观与形状(20℃)固体
Reaxys-RN1877474
PubChem物质ID87565935
SDBS (AIST Spectral DB)5587
MDL编号MFCD00007294

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 98.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point164.0 to 168.0 ℃

物性(参考值)

熔点165 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
386538J&K2-Chloro-5-nitrobenzoic Acid99%100元/25G;   169元/100G;   612元/500G;   展开

基本信息

分子式C7H4ClNO4
分子量201.56
熔点165-168
MDL编码MFCD00007294
Beilstein1877474
EINECS 编号219-739-7

安全信息

图形或危害标志
提示语Danger
危险说明H302
H315
H318
H335
H400
防范说明P261
P273
P280
P305+P351+P338
UN号码3077
危险分类9
包装等级III
WGK1
TSCA
A13754Alfa Aesar2-Chloro-5-nitrobenzoic Acid98+%383元/5g;   406元/100g;   1840元/500g;   展开

基本信息

MDL
MFCD00007294

EINECS
219-739-7

分子式
C7H4ClNO4

分子量
201.57

熔点
166-168°

闪点
>100°(212°F)

灵敏度
Ambient temperatures.

形态
Crystalline powder

Beilstein
1877474

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

C15469Alfa Aesar2-Chloro-5-nitrobenzoic Acid99+%881元/100g;   3209元/500g;   展开

基本信息

Ref#
15469

MDL
7294

分子式
C7 H4 Cl N O4

分子量
201.56

PHR1741Supelco2-Chloro-5-nitrobenzoic AcidPharmaceutical Secondary Standard; Certified Reference Material3096.84元/200 MG;   展开

产品说明

一般描述

2-Chloro-5-nitrobenzoic acid, commonly known as Mesalazine Impurity M, is a related compound of anti-inflammatory agent Mesalazine. Mesalazine belongs to a group of drugs referred to as aminosalicylates and is generally used in the treatment of inflammatory bowel disease.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
2-Chloro-5-nitrobenzoic acid may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7964 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式ClC6H3(NO2)CO2H
分子量201.56
Beilstein1877474
EC 号219-739-7
MDL编号MFCD00007294
PubChem化学物质编号329823586
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 200 mg
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp165-168 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-30℃
SMILES stringOC(=O)c1cc(ccc1Cl)[N+]([O-])=O
InChI1S/C7H4ClNO4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3H,(H,10,11)
InChI keyQUEKGYQTRJVEQC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H317 - H319
预防措施声明P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
079108Fluorochem2-Chloro-5-nitrobenzoic Acid95%220元/25g;   440元/100g;   展开

基本信息

CAS Number2516-96-3
MDL NumberMFCD00007294

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H400: Very toxic to aquatic life.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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