| CAS: | 2474876-09-8 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||
| G969942 | MACKLIN | GSK046 | 99% | 2498元/5mg; | 展开 | ||||||||||||||||||||||||
储存:-20°C | |||||||||||||||||||||||||||||
| SML3147 | Sigma-Aldrich | GSK046 | ≥98% (HPLC) | 1572.9元/; 6314.76元/; | 展开 | ||||||||||||||||||||||||
产品说明 生化/生理作用 GSK046 (iBET-BD2) is a potent and highly selective inhibitor of bromodomain BD2 of BRD2, BDR3, BRD4, BRDT. GSK046 inhibits the production of effector cytokines, including IFN-g, interleukin- 17A (IL-17A), and IL-22 in primary CD4+ T cell cultures without effecting proliferation. It appears that BD2-selective inhibition by GSK046 specifically affects the induction of gene expression while leaving the maintenance of established transcription programs largely unaltered. 基本信息
产品性质
安全信息
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