| CAS: | 2470424-39-4 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||
| SML2951 | Sigma-Aldrich | SGC-CK2-1 | ≥98% (HPLC) | 1260.64元/5 MG; 5054.12元/25 MG; | 展开 | ||||||||||||||||||||||||||
产品说明 生化/生理作用 SGC-CK2-1 is a potent and highly selective casein 2 (CK2, CKII) inhibitor (CK2α/CK2α′ IC50 = 4.2/2.3 nM by cell-free enzyme assay; DYRK2 IC50 = 440 nM, IC50≥3.4 μM against 465 other kinases). Unlike less specific CK2 inhibitors, SGC-CK2-1 shows no antiproliferation activity in HCT116 or U-87 MG cancer cultures (up to 10 μM) despite its potent cellular activity (CK2α/CK2α′ IC50 = 36/16 nM by cellular NanoBRET assay). 基本信息
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