| CAS: | 2088179-99-9 | ||
| 分子式: | C24H26ClN7O | ||
| 分子量: | 463.96 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||
| S937677 | MACKLIN | SM1-71 | ≥96% | 800元/5mg; 2500元/25mg; 6501元/100mg; | 展开 | ||||||||||||||||||||||||||
储存：2-8°C，密封，干燥 状态：固体 | |||||||||||||||||||||||||||||||
| SML2738 | Sigma-Aldrich | SM1-71 | ≥98% (HPLC) | 877.82元/5 MG; 3539.04元/25 MG; | 展开 | ||||||||||||||||||||||||||
产品说明 生化/生理作用 SM1-71 is a cell penetrant and potent multi-targeted kinase inhibitor that engages kinases through both reversible and irreversible binding. SM1-71 covalently inhibits 23 kinases including MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK(MLTK), MAP3K1, LIMK1, and RSK2. It binds to the cysteine located in vicinity of active site. In some cases, SM1-71 might bind to Cys located at allosteric places. SM1-71 potently inhibits growth of multiple cancer cell lines. 基本信息
产品性质
安全信息
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