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CAS: 204140-01-2
分子式: C25H25N3O6S
分子量: 495.6
中文名称: 
mmp-9/mmp-13 抑制剂 i
英文名称: 
mmp-9/mmp-13 inhibitor i
n-hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide
用途: MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both).
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M912043MACKLINMMP-9/MMP-13 Inhibitor I98%4029元/5mg;   展开
储存:-20°C,密闭,干燥
444252MilliporeMMP-9/MMP-13 Inhibitor I-CAS 204140-01-2-CalbiochemThe MMP-9/MMP-13 Inhibitor I, also referenced under CAS 204140-01-2, controls the biological activity of MMP-9/MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applicati2096.01元/1 MG;   展开

产品说明

一般描述

A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC50 = 900 pM) and MMP-13 (IC50 = 900 pM). Inhibits MMP-1 and MMP-3 at much higher concentrations (IC50 = 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50 = 930 nM).
A cell-permeable and highly, piperazine-based potent inhibitor of MMP-9 (IC50 = 900 pM) and MMP-13 (IC50 = 900 pM). Inhibits MMP-1 and MMP-3 at much higher concentrations (IC50 = 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50 = 930 nM).

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Primary Target
MMP-9
Product does not compete with ATP.
Reversible: no
Target IC50: 900 pM against both MMP-9 and MMP-13

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Cheng, M., et al. 2000. J. Med. Chem.43, 369.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C25H25N3O6S
分子量495.55

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white
溶解性methanol: 1 mg/mL
DMSO: 100 mg/mL
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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