| CAS: | 181632-25-7 | ||
| 分子式: | C21H19ClN4O2 | ||
| 分子量: | 394.85 | ||
| 英文名称: |
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| 用途: | SB 242084是5-HT2C选择性抑制剂，pKi值9.0，对5-HT2A和5-HT2B作用弱100倍以上。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||
| S881180 | MACKLIN | SB 242084 | ≥99% | 776元/5mg; 1109元/10mg; | 展开 | ||||||||||||||||||||||||||||||
储存：2-8℃ 状态：灰白色到粉色固体 | |||||||||||||||||||||||||||||||||||
| 5.06417 | Sigma-Aldrich | SB 242084 Hydrochloride-CAS 181632-25-7-Calbiochem | 2442.83元/10 MG; | 展开 | |||||||||||||||||||||||||||||||
产品说明 一般描述 A selective, brain-penetrant 5-HT2C receptor antagonist (pKi 8.2-9.0 ), with some effects on the 5-HT2B receptor (pKi 6.8-7.0) and 5-HT2A receptor (pKi 6.1-6.8). SB 242084 has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242,084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines. In vivo (ocular) IC50 values reported at 2.08 µM. 生化/生理作用 Primary Target 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Manvich, D. F., et al. 2012. J Pharmacol. Exp. Ther.342, 761. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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