CAS 1190217-35-6; asp7663

CAS:

1190217-35-6

分子式:

C₁₄H₁₄FNO₃

分子量:

263.26

英文名称:

asp7663

(e)-[7-fluoro-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3h-indol-3-ylidene]acetic acid

(2e)-2-[7-fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3h-indol-3-ylidene]acetic acid

用途:

(2E)-(7-Fluoro-1-isobutyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)acetic acid

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

A910445

MACKLIN

ASP 7663

98%

1328元/10mg;

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储存：-20°C，密闭，干燥

SML1467

Sigma-Aldrich

ASP7663

≥98% (HPLC)

1260.64元/5 MG; 5077.25元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC₅₀ values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.

基本信息

经验(实验)分子式	C₁₄H₁₄FNO₃
分子量	263.26
PubChem化学物质编号	329825901
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	light orange to dark orange
溶解性	DMSO: 25 mg/mL, clear
储存温度	2-8℃
SMILES string	CC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O
InChI	1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
InChI key	RCVZUIGCNAAMIC-UXBLZVDNSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable