CAS 104227-87-4; 泛昔洛韦; famciclovir

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

F795475

MACKLIN

Famciclovir

10mM in DMSO

185元/1ml;

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储存：-20°C

F0842

TCI

Famciclovir

>98.0%(T)(HPLC)

150元/500MG; 1290元/5G;

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基本信息

纯度/分析方法	>98.0%(T)(HPLC)
分子式/分子量	C₁₄H₁₉N₅O₄ = 321.34
外观与形状(20℃)	固体
储存温度	0-10℃
应避免的情况	加热
Reaxys-RN	4208403
PubChem物质ID	160871205
MDL编号	MFCD00866964

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 98.0 area%
Purity(Nonaqueous Titration)	min. 98.0 %
Melting point	103.0 to 107.0 ℃

物性(参考值)

熔点	105 ℃
最大吸收波长	310(EtOH) nm
水溶性	微溶
溶解性(可溶于)	甲醇,乙醇

相关法规

RTECS#

TY3164000

576433

J&K

Famciclovir

98%, 鸟嘌呤类似物抗病毒药物

776元/1g; 2233元/5G;

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基本信息

分子式	C₁₄H₁₉N₅O₄
分子量	321.34
熔点	103-107
MDL编码	MFCD00866964
Beilstein	4208403
存储条件	Store at 2-8℃

安全信息

防范说明	P262
WGK	3
RTECS	TY3164000

C46317

Alfa Aesar

Famciclovir

1534元/1g; 6012元/5g;

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基本信息

Ref#
46317

分子式
C14H19N5O4

分子量
585.65

PHR1696

Supelco

Famciclovir

Pharmaceutical Secondary Standard; Certified Reference Material

2191.84元/1 G;

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产品说明

一般描述

Famciclovir is an antiviral drug, which is predominantly used in the treatment of herpes virus infection. It is an inactive prodrug, which on administration, undergoes rapid biotransformation to penciclovir.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Famciclovir may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography.

生化/生理作用

泛昔洛韦是一种抗逆转录病毒鸟苷类似物，用于治疗疱疹病毒感染和乙肝。泛昔洛韦可迅速转化为喷昔洛韦。病毒胸苷激酶将喷昔洛韦磷酸化为单磷酸形式，然后细胞激酶又将其转换为三磷酸喷昔洛韦。喷昔洛韦三磷酸可竞争性抑制病毒 DNA 聚合酶，从而抑制病毒复制。长时间服用会形成耐药性；这通常表现为筛选出了一批 DNA 聚合酶基因逆转录酶结构域突变的预先存在的耐药性菌株。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC3254 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₁₄H₁₉N₅O₄
分子量	321.33
MDL编号	MFCD00866964
PubChem化学物质编号	329823560
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
包装	pkg of 1 g
technique(s)	HPLC: suitable gas chromatography (GC): suitable
application(s)	pharmaceutical (small molecule)
格式	neat
药典可追溯性	traceable to USP 1269152
储存温度	2-8℃
SMILES string	CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InChI	1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChI key	GGXKWVWZWMLJEH-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

F7932

Sigma-Aldrich

Famciclovir

≥98% (HPLC)

837.34元/10 MG;

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产品说明

应用

泛昔洛韦用于疱疹病毒感染和乙肝药物开发研究。它可用作参考化合物。泛昔洛韦可用于研究控制转化为喷昔洛韦和其他代谢物的因素。

包装

10, 50 mg in glass bottle

生化/生理作用

特点和优势

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF (F7932.pdf )中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

基本信息

经验(实验)分子式	C₁₄H₁₉N₅O₄
分子量	321.33
MDL编号	MFCD00866964
PubChem化学物质编号	329799767
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
储存条件	desiccated
溶解性	DMSO: ≥10 mg/mL
创始人	Novartis
储存温度	2-8℃
SMILES string	CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InChI	1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChI key	GGXKWVWZWMLJEH-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1269152

USP

Famciclovir

United States Pharmacopeia (USP) Reference Standard

3231.47元/200 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₄H₁₉N₅O₄
分子量	321.33
MDL编号	MFCD00866964
PubChem化学物质编号	329749829
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
InChI	1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
InChI key	GGXKWVWZWMLJEH-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable